Hypnotic Relaxation Therapy for Reduction of Hot Flashes in Postmenopausal Women: Examination of Cortisol as a Potential Mediator

被引:4
作者
Kendrick, Cassie [1 ]
Johnson, Aimee K. [1 ]
Sliwinski, Jim [1 ]
Patterson, Vicki [1 ]
Fisher, William I. [1 ]
Elkins, Gary R. [1 ]
Carpenter, Janet S. [2 ]
机构
[1] Baylor Univ, Waco, TX 76798 USA
[2] Indiana Univ, Sch Nursing, Indianapolis, IN 46204 USA
基金
美国国家卫生研究院;
关键词
CLINICAL HYPNOSIS; BREAST-CANCER; SYMPTOMS; ANXIETY; HEALTH; FLUOXETINE; PHYSIOLOGY; PAROXETINE; IMPACT; LIFE;
D O I
10.1080/00207144.2014.931169
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
Hypnotic relaxation therapy (HRT) has been shown to reduce hot flashes in postmenopausal women and breast cancer survivors. While the biological mechanism by which HRT reduces hot flashes is unknown, it has been speculated that reduction of stress mediates the intervention's effectiveness. The purpose of the present study was to examine the effect of HRT on a known biomarker of stress (cortisol) and changes in cortisol as a mediator. Sixty-two postmenopausal women received hypnotic relaxation therapy for hot flashes and completed measures of hot flashes in addition to providing cortisol samples at baseline and endpoint. HRT resulted in significantly decreased early evening salivary cortisol concentrations. However, changes in salivary cortisol concentrations did not mediate the effects of HRT.
引用
收藏
页码:76 / 91
页数:16
相关论文
共 45 条
[1]   THE MODERATOR MEDIATOR VARIABLE DISTINCTION IN SOCIAL PSYCHOLOGICAL-RESEARCH - CONCEPTUAL, STRATEGIC, AND STATISTICAL CONSIDERATIONS [J].
BARON, RM ;
KENNY, DA .
JOURNAL OF PERSONALITY AND SOCIAL PSYCHOLOGY, 1986, 51 (06) :1173-1182
[2]   The role of serotonin in hot flushes [J].
Berendsen, HHG .
MATURITAS, 2000, 36 (03) :155-164
[3]   Symptoms and treatment in cancer therapy-induced early menopause [J].
Boekhout, Annelies H. ;
Beijnen, Jos H. ;
Schellens, Jan H. M. .
ONCOLOGIST, 2006, 11 (06) :641-654
[4]  
Bromberger JT, 2013, MENOPAUSE, V20, P488, DOI [10.1097/gme.0b013e3182730599, 10.1097/GME.0b013e3182730599]
[5]  
Carpenter Janet S, 2002, Oncol Nurs Forum, V29, pE16, DOI 10.1188/02.ONF.E16-E25
[6]   The hot flash related daily interference scale: A tool for assessing the impact of hot flashes on quality of life following breast cancer [J].
Carpenter, JS .
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT, 2001, 22 (06) :979-989
[7]  
Carpenter JS, 1998, CANCER-AM CANCER SOC, V82, P1682, DOI 10.1002/(SICI)1097-0142(19980501)82:9<1682::AID-CNCR14>3.3.CO
[8]  
2-8
[9]   Skin blood flow in adult human thermoregulation: How it works, when it does not, and why [J].
Charkoudian, N .
MAYO CLINIC PROCEEDINGS, 2003, 78 (05) :603-612
[10]   The Potential Role of Glucose Transport Changes in Hot Flash Physiology: A Hypothesis [J].
Dormire, Sharon L. .
BIOLOGICAL RESEARCH FOR NURSING, 2009, 10 (03) :241-247