Pregnancy and perinatal outcomes among women with multiple sclerosis: a retrospective case-controlled study in South Hungary

被引：9

作者：

Vanya, Melinda ^{[1
]}

Nyari, Tibor ^{[2
]}

Bencsik, Krisztina ^{[3
]}

Bartfai, Gyoergy ^{[1
]}

机构：

[1] Univ Szeged, Dept Obstet & Gynaecol, Fac Gen Med, H-6725 Szeged, Hungary

[2] Univ Szeged, Dept Phys & Informat, Fac Gen Med, H-6725 Szeged, Hungary

[3] Univ Szeged, Dept Neurol, Fac Gen Med, Albert Szent Gyorgyi Clin Ctr, H-6725 Szeged, Hungary

来源：

JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE | 2014年 / 27卷 / 06期

关键词：

Intrauterine death; miscarriage; multiple sclerosis; treatment-naive pregnancy; DIAGNOSTIC-CRITERIA; POPULATION; PREVALENCE; DELIVERY; DISEASE; RISK;

D O I：

10.3109/14767058.2013.825596

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Objective: The aim of this study was to investigate the connections between multiple sclerosis (MS) and fertility, pregnancy. Methods: The case histories and pregnancy complications in a sample of 65 treatment-naive pregnant women with MS in the period 1998-2012 were compared with an age-matched case-controlled analysis. Comparisons were made between primigravidas and multigravidas subjects. Results: Our results revealed a higher rate of miscarriage (18.46%) in the first trimester in women with MS, and intrauterine death (7.69%) in the third trimester, as compared with women without MS (p<0.001 and p = 0.035). Conclusions: These findings suggest that, the risk of miscarriages and intrauterine death may be disease-related not drug-related feature. Further studies are needed to determine to possible associated factors of miscarriages.

引用

页码：577 / 581

页数：5