Assessment of the Acute Toxicity and Analgesic Activity of Ethyl-6-Amino-4-Aryl-5-Cyano-2,4-Dihydropyrano-2,3-C]-Pyrazole-3-Carboxylates

被引：10
|
作者：
Gein, O. N. [1 ]
Zamaraeva, T. M. [1 ]
Gein, V. L. [1 ]
机构：
[1] Minist Hlth Russian Federat, Perm State Pharmaceut Acad, 2 Polevaya St, Perm 614990, Russia
来源：
PHARMACEUTICAL CHEMISTRY JOURNAL | 2019年 / 53卷 / 01期
关键词：
pyranopyrazoles; ethyl-6-amino-4-aryl-5-cyano-2; 4-dihydropyrano[2,3-c]pyrazole-3-carboxylates; acute toxicity; analgesic activity; DERIVATIVES;
D O I：
10.1007/s11094-019-01952-x
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The acute toxicity and analgesic activity of compounds of the ethyl-6-amino-4-aryl-5-cyano-2,4-dihydropyrano[2,3-c]pyrazole-3-carboxylate series were investigated. Study compounds were found to be essentially nontoxic and to have analgesic activity.
引用
收藏
页码：40 / 42
页数：3
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