Sib-pair analysis of the Collaborative Study on the Genetics of Alcoholism data set

被引:0
作者
Jorgenson, E [1 ]
Hinds, D [1 ]
Risch, N [1 ]
机构
[1] Stanford Univ, Med Ctr, Dept Genet, Sch Med, Stanford, CA 94305 USA
关键词
affected sibling-pair linkage analysis; linkage analysis; nonparametric;
D O I
暂无
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Nonparametric sib-pair analysis was performed on the Collaborative Study on the Genetics of Alcoholism data set. Concordant and discordant pair groups were examined using the ASPEX package of programs. Allele sharing and multipoint lod scores for six comparison groups were obtained. Sharing and lod score patterns were not consistent with a simple genetic interpretation. (C) 1999 Wiley-Liss, Inc.
引用
收藏
页码:S187 / S191
页数:5
相关论文
共 23 条
  • [1] A multiple locus analysis of the collaborative study on the genetics of alcoholism data set
    Lin, SL
    Irwin, ME
    Wright, FA
    GENETIC EPIDEMIOLOGY, 1999, 17 : S229 - S234
  • [2] Diagnosis as a covariate in sib-pair linkage analysis
    Rice, JP
    AMERICAN JOURNAL OF MEDICAL GENETICS, 2001, 105 (01): : 55 - 56
  • [3] Optimal weighting scheme for affected sib-pair analysis of sibship data
    Sham, PC
    Zhao, JH
    Curtis, D
    ANNALS OF HUMAN GENETICS, 1997, 61 : 61 - 69
  • [4] PATH-ANALYSIS AND SIB-PAIR LINKAGE
    CAREY, G
    WILLIAMSON, JA
    GENETIC EPIDEMIOLOGY, 1993, 10 (02) : 103 - 112
  • [5] Gamma Mixed Model to Improve Sib-Pair Linkage Analysis
    Kim, Jeonghwan
    Suh, Young Ju
    Won, Sungho
    Nah, Jeung Weon
    Lee, Woojoo
    KOREAN JOURNAL OF APPLIED STATISTICS, 2015, 28 (02) : 221 - 230
  • [6] MULTIPLE-REGRESSION ANALYSIS OF SIB-PAIR DATA ON READING TO DETECT QUANTITATIVE TRAIT LOCI
    FULKER, DW
    CARDON, LR
    DEFRIES, JC
    KIMBERLING, WJ
    PENNINGTON, BF
    SMITH, SD
    READING AND WRITING, 1991, 3 (3-4) : 299 - 313
  • [7] Haseman and Elston Sib-Pair Linkage Analysis: A Brief Historical Note
    John C. DeFries
    Behavior Genetics, 2010, 40 : 1 - 2
  • [8] Multiple regression approach to mapping of quantitative trait loci (QTL) based on sib-pair data: A theoretical analysis
    Xiong, MM
    Guo, SW
    ANNALS OF STATISTICS, 2000, 28 (05) : 1245 - 1278
  • [9] Mathematical basis of affected sib-pair analysis: an extension to X-linked loci
    Tsukamoto, Yasuo
    Komai, Koichiro
    Tsumiyama, Ken
    Sakai, Yoshitada
    Shiozawa, Shunichi
    MODERN RHEUMATOLOGY, 2010, 20 (04) : 370 - 375
  • [10] Improved power of sib-pair linkage analysis using measures of complex trait dynamics
    Moore, JH
    HUMAN HEREDITY, 2001, 52 (02) : 113 - 115