Squamous cell carcinoma arising in a ciliated hepatic foregut cyst: Case report and literature review

被引：24

作者：

Zhang, Xiangsheng ^{[1
]}

Wang, Zhen ^{[1
]}

Dong, Yanjun ^{[1
]}

机构：

[1] Cleveland Clin, Dept Clin Pathol, Cleveland, OH 44195 USA

来源：

PATHOLOGY RESEARCH AND PRACTICE | 2009年 / 205卷 / 07期

关键词：

Liver; Foregut cyst; Squamous cell carcinoma;

D O I：

10.1016/j.prp.2008.12.003

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

We report a case of squamous cell carcinoma arising in a ciliated hepatic foregut cyst (CHFC) in the left lobe of the liver in a 60-year-old woman. Gross examination revealed an irregular, partially encapsulated, smooth tumor mass with multiple cystic areas, 3-5 mm in size. Microscopically, the lining of the microcysts was composed of ciliated columnar epithelium with scattered goblet cells. Multiple foci of squamous metaplasia of the columnar epithelium were observed, which showed areas with dysplastic changes and other areas with carcinomatous transformation. Our case also showed an inconspicuous or absent smooth muscle layer. This case suggests that CHFC deserves careful clinical follow-up and differential diagnosis to exclude malignant transformation. Total surgical excision of the cyst is recommended. (C) 2009 Elsevier GmbH. All rights reserved.

引用

页码：498 / 501

页数：4

共 7 条

[1] Squamous cell carcinoma arising in a hepatic forgut cyst [J].

de Lajarte-Thirouard, AS ;

Rioux-Leclercq, N ;

Boudjema, K ;

Gandon, Y ;

Ramée, MP ;

Turlin, B .

PATHOLOGY RESEARCH AND PRACTICE, 2002, 198 (10) :697-700

[2] Squamous cell carcinoma arising in a ciliated hepatic foregut cyst [J].

Furlanetto, A ;

Tos, APD .

VIRCHOWS ARCHIV, 2002, 441 (03) :296-298

[3]

Jakowski Joseph D, 2004, Ann Diagn Pathol, V8, P342, DOI 10.1053/j.anndiagpath.2004.08.004

[4] Ciliated hepatic cyst without smooth muscle layer: A variant of ciliated hepatic foregut cyst? [J].

Sato, Yasunori ;

Kitagawa, Satoshi ;

Zen, Yoh ;

Minato, Hiroshi ;

Nakanuma, Yasuni .

PATHOLOGY INTERNATIONAL, 2006, 56 (06) :340-344

[5]

Vick DJ, 1999, ARCH PATHOL LAB MED, V123, P1115

[6] Ciliated hepatic foregut cyst - A study of six cases and review of the literature [J].

Vick, DJ ;

Goodman, ZD ;

Deavers, MT ;

Cain, J ;

Ishak, KG .

AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1999, 23 (06) :671-677

[7] CILIATED HEPATIC FOREGUT CYST [J].

WHEELER, DA ;

EDMONDSON, HA .

AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1984, 8 (06) :467-470

← 1 →