Daphnezomines T-V, Alkaloids from Daphniphyllum humile

被引：8

作者：

Kubota, Takaaki ^{[1
]}

Suzuki, Teppei ^{[1
]}

Ishiuchi, Kan'ichiro ^{[1
]}

Kuhara, Taiga ^{[2
]}

Kobayashi, Jun'ichi ^{[1
]}

机构：

[1] Hokkaido Univ, Grad Sch Pharmaceut Sci, Sapporo, Hokkaido 060812, Japan

[2] Niigata Prefectural Bot Garden, Niigata 9500845, Japan

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2009年 / 57卷 / 05期

关键词：

Daphniphyllum alkaloid; Daphniphyllum humile; daphnezomine T; daphnezomine U; daphnezomine V; CORE; CASCADE; MOIETY;

D O I：

10.1248/cpb.57.504

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Three new Daphniphyllum alkaloids, daphnezomines T-V (1-3), were isolated from the leaves and branches of Daphniphyllum humile (Daphniphyllaceae). The structures and relative stereochemistry of 1-3 were elucidated on the basis of spectroscopic data. Daphnezomine T (1) is the first alkaloid without a branched C-1 unit at C-5 among all Daphiniphyllum alkaloids reported so far.

引用

页码：504 / 507

页数：4

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