Stability of Lipid-membrane-incorporated Azobenzene and Pyrenes in Water

被引:11
作者
Ikeda, Atsushi [1 ]
Hida, Tomohiro [2 ]
Nakano, Toshiyuki [2 ]
Hino, Shodai [1 ,2 ]
Nobusawa, Kazuyuki [2 ]
Akiyama, Motofusa [2 ,3 ]
Sugikawa, Kouta [1 ]
机构
[1] Hiroshima Univ, Grad Sch Engn, Dept Appl Chem, Hiroshima 7398527, Japan
[2] Nara Inst Sci & Technol, Grad Sch Mat Sci, Nara 6300192, Japan
[3] Chuo Univ, Fac Sci & Engn, Dept Appl Chem, Bunkyo Ku, Tokyo 1138551, Japan
基金
日本学术振兴会;
关键词
MOLECULAR-DYNAMICS SIMULATION; PHOTODYNAMIC THERAPY; C-60; FULLERENES; EXCHANGE METHOD; LIPOSOMES; BILAYER; TRANSLOCATION; PHOTOCLEAVAGE; VESICLES; MODEL;
D O I
10.1246/cl.140595
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Small hydrophobic planar pi-conjugated molecules such as azobenzene or pyrene do not need chemical modifications to exhibit affinity toward the lipid membranes. Liposomes incorporating these molecules are stable in aqueous solution for up to 1 month.
引用
收藏
页码:1551 / 1553
页数:3
相关论文
共 37 条
[1]   Drug delivery systems: Entering the mainstream [J].
Allen, TM ;
Cullis, PR .
SCIENCE, 2004, 303 (5665) :1818-1822
[2]  
Bangham A D, 1968, Prog Biophys Mol Biol, V18, P29, DOI 10.1016/0079-6107(68)90019-9
[3]   Passive transport of C60 fullerenes through a lipid membrane:: A molecular dynamics simulation study [J].
Bedrov, Dmitry ;
Smith, Grant D. ;
Davande, Hemali ;
Li, Liwei .
JOURNAL OF PHYSICAL CHEMISTRY B, 2008, 112 (07) :2078-2084
[4]   Probing the Perturbation of Lecithin Bilayers by Unmodified C60 Fullerenes Using Experimental Methods and Computational Simulations [J].
Bouropoulos, Nikolaos ;
Katsamenis, Orestis L. ;
Cox, Paul A. ;
Norman, Simon ;
Kallinteri, Paraskevi ;
Favretto, Marco E. ;
Yannopoulos, Spyros N. ;
Bakandritsos, Aristides ;
Fatouros, Dimitrios G. .
JOURNAL OF PHYSICAL CHEMISTRY C, 2012, 116 (06) :3867-3874
[5]   Calorimetric approach of the interaction and absorption of polycyclic aromatic hydrocarbons with model membranes [J].
Castelli, F ;
Librando, V ;
Sarpietro, MG .
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2002, 36 (12) :2717-2723
[6]   The interaction of C60 and its derivatives with a lipid bilayer via molecular dynamics simulations [J].
D'Rozario, Robert S. G. ;
Wee, Chze Ling ;
Wallace, E. Jayne ;
Sansom, Mark S. P. .
NANOTECHNOLOGY, 2009, 20 (11)
[7]   Intracellular Uptake and Photodynamic Activity of Water-Soluble [60]- and [70]Fullerenes Incorporated in Liposomes [J].
Doi, Yuki ;
Ikeda, Atsushi ;
Akiyama, Motofusa ;
Nagano, Mai ;
Shigematsu, Tamami ;
Ogawa, Takuya ;
Takeya, Tatsuo ;
Nagasaki, Takeshi .
CHEMISTRY-A EUROPEAN JOURNAL, 2008, 14 (29) :8892-8897
[8]   Photodynamic therapy [J].
Dougherty, TJ ;
Gomer, CJ ;
Henderson, BW ;
Jori, G ;
Kessel, D ;
Korbelik, M ;
Moan, J ;
Peng, Q .
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1998, 90 (12) :889-905
[9]   Photofunctional vesicles containing prussian blue and azobenzene [J].
Einaga, Y ;
Sato, O ;
Iyoda, T ;
Fujishima, A ;
Hashimoto, K .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (15) :3745-3750
[10]   LIPOFECTION - A HIGHLY EFFICIENT, LIPID-MEDIATED DNA-TRANSFECTION PROCEDURE [J].
FELGNER, PL ;
GADEK, TR ;
HOLM, M ;
ROMAN, R ;
CHAN, HW ;
WENZ, M ;
NORTHROP, JP ;
RINGOLD, GM ;
DANIELSEN, M .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (21) :7413-7417