The Use of Ammonia as an Ultimate Amino Source in the Transition Metal-Catalyzed C-H Amination

被引：95

作者：

Kim, Hyunwoo ^{[1
,2
]}

Chang, Sukbok ^{[1
,2
]}

机构：

[1] Korea Adv Inst Sci Technol KAIST, Dept Chem, Daejeon 34141, South Korea

[2] Inst Basic Sci IBS, Ctr Catalyt Hydrocarbon Functionalizat, Daejeon 34141, South Korea

来源：

ACCOUNTS OF CHEMICAL RESEARCH | 2017年 / 50卷 / 03期

关键词：

HYDROGEN BONDS; DERIVATIVES; DINITROGEN; CLEAVAGE; AGENTS;

D O I：

10.1021/acs.accounts.6b00489

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The development of efficient and elective transition metal catalyst systems enabling a direct C-H amination of hydrocarbons using ammonia is highly desirable considering the fact that ammonia is the most readily available nitrogen source. It is anticipated that a new mechanistic scaffold distinct from the currently applicable ones will guide this research eventually to have broad applicability in synthetic methodology, medicinal chemistry, and materials science.

引用

页码：482 / 486

页数：5

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