Successful treatment for cryptococcal meningoencephalitis complicated by cerebral salt-wasting syndrome in a patient with chronic lymphocytic leukemia: A clinical case

被引:0
作者
Potapenko, V. G. [1 ,2 ]
Konovalenko, I. B. [1 ]
Oksema, E. V. [1 ]
Filippova, L. N. [1 ]
Dulaeva, E. N. [1 ]
Derevyannykh, N. A. [1 ]
Krasnoruzhsky, A. I. [1 ]
Klimovich, A. V. [1 ]
Klimko, N. N. [3 ]
Medvedeva, N. V. [1 ]
机构
[1] City Clin Hosp Thirty One, St Petersburg, Russia
[2] Acad IP Pavlov First St Petersburg State Med Univ, Minist Hlth Russia, St Petersburg, Russia
[3] II Mechnikov North Western State Med Univ, PN Kashkin Res Inst Med Mycol, Minist Hlth Russia, St Petersburg, Russia
关键词
Cryptococcus; meningoencephalitis; cerebral salt-wasting syndrome; amphotericin B; chronic lymphocytic leukemia; HYPONATREMIA; MENINGITIS; MANAGEMENT;
D O I
10.17116/terarkh2015871199-102
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Cryptococcus neoformans is a common agent of fungal meningoencephalitis in immunocompromised patients. Cerebral salt-wasting syndrome is one of the rare causes of severe hyponatremia in patients with CNS diseases. The paper describes the first clinical case of a patient, whose onset of chronic lymphocytic leukemia was complicated by cryptococcal meningoencephalitis presenting with mental disorders and severe electrolytic imbalance. Antifungal treatment with amphotericin B and fluconazole could alleviate an infectious process and metabolic disturbances.
引用
收藏
页码:99 / 102
页数:4
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