Physical properties and biocompatibility of an injectable calcium-silicate-based root canal sealer: in vitro and in vivo study

被引：60

作者：

Lim, Eun-Su ^{[1
,2
,3
]}

Park, Young-Bae ^{[1
,2
]}

Kwon, Young-Sun ^{[1
,2
]}

Shon, Won-Jun ^{[4
,5
]}

Lee, Kwang-Won ^{[1
,2
,3
]}

Min, Kyung-San ^{[1
,2
,3
]}

机构：

[1] Chonbuk Natl Univ, Sch Dent, Dept Conservat Dent, Jeonju Si 54896, South Korea

[2] Chonbuk Natl Univ, Inst Oral Biosci, Jeonju Si 54896, South Korea

[3] Chonbuk Natl Univ, Chonbuk Natl Univ Hosp, Biomed Res Inst, Res Inst Clin Med, Jeonju Si 54907, South Korea

[4] Seoul Natl Univ, Dent Res Inst, Dept Conservat Dent, Seoul 03080, South Korea

[5] Seoul Natl Univ, Sch Dent, Seoul 03080, South Korea

来源：

BMC ORAL HEALTH | 2015年 / 15卷

关键词：

Injectable; Calcium silicate; Root canal sealer; Physical; Biological; MINERAL TRIOXIDE AGGREGATE; END FILLING MATERIAL; PORTLAND-CEMENT; PHYSICOCHEMICAL PROPERTIES; ENDODONTIC SEALERS; TISSUE-RESPONSE; BISMUTH OXIDE; MTA; CYTOTOXICITY; SOLUBILITY;

D O I：

10.1186/s12903-015-0112-9

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Background: The aim of this study was to investigate the physical properties and biological effects of an experimentally developed injectable premixed calcium-silicate root canal sealer (Endoseal) in comparison with mineral trioxide aggregate (MTA) and a resin-based sealer (AHplus). Methods: The pH, solubility, dimensional change, flow, and radiopacity of the materials were evaluated. Biocompatibility was evaluated on the basis of cell morphology and a viability test using MC3T3-E1 cells. For evaluate inflammatory reaction, the tested sealers were implanted into dorsal subcutaneous connective tissue of Sprague Dawley rats. After 7 days, the implants with the surrounding tissue were retrieved, and histological evaluation was performed. Results: Endoseal showed high alkalinity similar to that of MTA. The solubility of the tested materials was similar. The dimensional change and flow of Endoseal was significantly higher than that of other materials (P < 0.05). The radiopacity of Endoseal was lower than that of AHplus (P < 0.05). The biocompatibility was similar to those of MTA. Inflammatory reaction of Endoseal was similar with that of MTA, but lower than that of AHplus (P < 0.05). Conclusions: The present study indicates that Endoseal has favorable physical properties and biocompatibility. Therefore, we suggest that Endoseal has the potential to be used as a predictable root canal sealer.

引用

页数：7

共 39 条

[1] Filling of artificial lateral canals and microleakage and flow of five endodontic sealers [J].