Profuse haematochezia related to Crohn's disease: a rare case report

被引:0
作者
Paramita, Dilly Niza [1 ]
Widodo, Budi [2 ]
Heriyawati [3 ]
机构
[1] Univ Airlangga, Dept Internal Med, Internal Med, Fac Med,Dr Soetomo Gen Acad Hosp, Surabaya 60286, Indonesia
[2] Univ Airlangga Univ, Dr Soetomo Gen Acad Hosp, Dept Internal Med, Dev Gastroenterol Hepatol,Fac Med, Surabaya 60286, Indonesia
[3] Univ Airlangga Univ, Dr Soetomo Gen Acad Hosp, Dept Anat Pathol, Fac Med, Surabaya 60286, Indonesia
关键词
haematochezia; lower gastrointestinal bleeding; irritable bowel disease; Crohn's disease; GASTROINTESTINAL HEMORRHAGE; EPIDEMIOLOGY; DIAGNOSIS;
D O I
10.15562/bmj.v11i1.3204
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: Lower gastrointestinal bleeding (LGIB) can be caused by irritable bowel disease. Haematochezia is one of the LGIB symptoms. Profuse haematochezia is a rare complication in Crohn's disease. Case Presentation: We reported a 24-year-old patient with profuse haematochezia with severe anaemia and hypovolemic shock. Anamnesis, physical examination and colonoscopy showed that haematochezia was caused by Crohn's disease. Colonoscopy was done after the patient was hemodynamically stable with findings of external haemorrhoid and multiple ulcers with varying size (0.5-2 cm) on ascending colon, caecum and terminal ileum. The tissue histopathology of ileocecal junction indicated intestinal epithelia with partially eroded, crypts infiltrated by inflammatory cells, swollen lamina propria with proliferation and dilation of blood vessels indicting the Crohn's disease. The patient then treated with Crohn's disease medical therapy including low dose oral steroid, sulfasalazine and antibiotics. Clinical improvement was found on one week follow-up after discharge from hospital. Conclusion: Profuse haematochezia could be associated with Crohn's disease and the comprehensive approaches should be taken to manage the Crohn's disease with such presentation.
引用
收藏
页码:205 / 208
页数:4
相关论文
共 26 条
[1]   Lower GI Bleeding: An Update on Incidences and Causes [J].
Adegboyega, Titilayo ;
Rivadeneira, David .
CLINICS IN COLON AND RECTAL SURGERY, 2020, 33 (01) :28-34
[2]  
Amin SK, SPRINGERREFERENCE, DOI [10.1007/springerreference_108989, DOI 10.1007/SPRINGERREFERENCE_108989]
[3]   Epidemiology of lower gastrointestinal bleeding in China: Single-center series and systematic analysis of Chinese literature with 53 951 patients [J].
Bai, Yu ;
Peng, Jun ;
Gao, Jun ;
Zou, Duo-Wu ;
Li, Zhao-Shen .
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2011, 26 (04) :678-682
[4]  
BEST WR, 1976, GASTROENTEROLOGY, V70, P439
[5]  
Charilaou P, 2018, AM J GASTROENTEROL, V113, pS318
[6]   Approach to the Patient With Hematochezia [J].
Cotter, Thomas G. ;
Buckley, Niamh S. ;
Loftus, Conor G. .
MAYO CLINIC PROCEEDINGS, 2017, 92 (05) :797-804
[7]   Lower gastrointestinal bleeding in Crohn's disease: How (un-)common is it and how to tackle it? [J].
Daperno, Marco ;
Sostegni, Raffaello ;
Rocca, Rodolfo .
DIGESTIVE AND LIVER DISEASE, 2012, 44 (09) :721-722
[8]   Crohn's disease: a clinical update [J].
Ha, Francis ;
Khalil, Hanan .
THERAPEUTIC ADVANCES IN GASTROENTEROLOGY, 2015, 8 (06) :352-359
[9]   Epidemiology and clinical course of Crohn's disease: Results from observational studies [J].
Hovde, Oistein ;
Mourn, Bjorn A. .
WORLD JOURNAL OF GASTROENTEROLOGY, 2012, 18 (15) :1723-1731
[10]   Lower gastrointestinal bleeding: incidence, etiology, and outcomes in a population-based setting [J].
Hreinsson, Johann P. ;
Gudmundsson, Sveinn ;
Kalaitzakis, Evangelos ;
Bjoernsson, Einar S. .
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 2013, 25 (01) :37-43