Update on latest advances in time-of-flight PET

被引：65
作者：
Surti, Suleman [1 ]
Karp, Joel S. [1 ,2 ]
机构：
[1] Univ Penn, Dept Radiol, Philadelphia, PA 19104 USA
[2] Univ Penn, Perelman Sch Med, Dept Radiol, 154 John Morgan Bldg,3620 Hamilton Walk, Philadelphia, PA 19104 USA
来源：
PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS | 2020年 / 80卷
基金：
美国国家卫生研究院;
关键词：
Time-of-flight PET; Scintillator; SiPM; Coincidence timing resolution; DIGITAL SILICON PHOTOMULTIPLIER; SPATIAL-RESOLUTION; PERFORMANCE; DETECTOR; DESIGN; EFFICIENCY; SCANNER; DEPTH; SIPMS;
D O I：
10.1016/j.ejmp.2020.10.031
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
This paper provides an update on time-of-flight (TOF) PET with a focus on latest hardware developments leading to current commercial PET/CT instruments. We describe advances in scintillator development, new photosensors and associated electronics readout, and detector designs for utilization in complete systems. Next, we introduce the latest commercial PET/CT scanners based on the aforementioned technologies, and discuss the detector design choices made that are relevant to differences in the system performance. Finally, we end with a discussion of the latest performance benchmarks for improved timing in PET detectors, challenges in scaling this performance to a complete system, and the outlook towards achieving a sub-50 ps coincidence timing resolution (CTR) in a PET detector.
引用
收藏
页码：251 / 258
页数：8
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