Recent advances in engineered nanomaterials for acute kidney injury theranostics

被引：24
作者：
Wang, Lefeng [1 ,2 ]
Zhang, Yunjing [3 ]
Li, Yangyang [4 ]
Chen, Jianghua [1 ,2 ]
Lin, Weiqiang [3 ]
机构：
[1] Zhejiang Univ, Sch Med, Kidney Dis Ctr, Inst Nephrol,Affiliated Hosp 1, Hangzhou 310003, Zhejiang, Peoples R China
[2] Key Lab Kidney Dis Prevent & Control Technol, Hangzhou 310003, Zhejiang, Peoples R China
[3] Zhejiang Univ, Sch Med, Affiliated Hosp 4, Inst Translat Med, Jinhua 322000, Zhejiang, Peoples R China
[4] Zhejiang Univ, Sch Med, Womens Hosp, Key Lab Womens Reprod Hlth Res Zhejiang Prov, Hangzhou 310006, Peoples R China
来源：
NANO RESEARCH | 2021年 / 14卷 / 04期
基金：
中国国家自然科学基金; 国家重点研发计划;
关键词：
acute kidney injury; nanomaterials; early detection; therapy; translational applications; DNA ORIGAMI NANOSTRUCTURES; DRUG-DELIVERY-SYSTEM; IN-VITRO DIAGNOSTICS; BLACK PHOSPHORUS; RENAL INJURY; PHOTOACOUSTIC TOMOGRAPHY; POLYOXOMETALATE CLUSTER; MITOCHONDRIAL-FUNCTION; ILL PATIENTS; NANOPARTICLES;
D O I：
10.1007/s12274-020-3067-3
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
Acute kidney injury (AKI), has become the focus of increasing attention due to its high risk of death. The early diagnosis and treatment of AKI significantly reduce the risk of renal tissue damage and kidney dysfunction. However, the efficient early diagnosis and treatment approach for AKI remains a challenge. AKI screening via precise nanomaterial theranostics is a new alternative approach. This study summarizes the recent advances in functional nanomaterials in the early detection and treatment of AKI. The challenges and problems in the use of nanomaterials for AKI in clinical applications are also discussed. It is anticipated that highlighting these new advances will lay the foundation for further translational research on the promising application of nanomaterials for AKI.
引用
收藏
页码：920 / 933
页数：14
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