Selenium-Nitrogen Bond Cleavage in Selenazole Ring System with Grignard Reagent: A Convenient Synthesis of Unsymmetrically Substituted Selenides

被引：7

作者：

Lisiak, Rafal ^{[1
]}

Mlochowski, Jacek ^{[1
]}

机构：

[1] Wroclaw Univ Technol, Fac Chem, Dept Organ Chem, PL-50370 Wroclaw, Poland

来源：

SYNTHETIC COMMUNICATIONS | 2009年 / 39卷 / 17期

关键词：

Grignard reagents; heterocycles; selenenamides; selenides; DIORGANYL SELENIDES; ALLYLIC ALCOHOLS; SE-SE; SELENOXIDE; CONVERSION; OXIDATION; HALIDES; ANIONS; ACIDS;

D O I：

10.1080/00397910902730994

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

High reactivity of the selenenamide bond in selenazoles toward nucleophiles can be exploited for synthesis of other organoselenium compounds. It has been found that benzisoselenazol-3(2H)-ones and related selenaheterocycles with an Se-N moiety treated with Grignard reagent gave unsymmetrical aryl-aryl and aryl-alkyl selenides in moderate to good yields. This reaction has a synthetic value because it is highly selective and can be realized under mild conditions.

引用

页码：3141 / 3155

页数：15

共 29 条

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