Chitosan and its application in dental implantology

Objective: The aim of this review was to evaluate the properties of chitosan for an application in dental implantology. Methods: Electronic Databases: PubMed, Google Scholar, Scopus, were used to recherche the articles published from 2010 to 2021. The keywords used were: chitosan, biocompatible, antibacterial, osseointegration, implant, bioactive. After a carefully selection according to the above keywords 46 articles met the condition to be studied Results: Chitosan is a biopolymer, that can be easy produced. Its antibacterial, anti-inflammatory, anti-fugal, hemostatic, analgesic, mucoadhesive, osseointegrative properties and its excellent film-forming ability make chitosan a material with a future in dental implantology and in other areas of dental applications. Titan implants coated with chitosan showed better bioactive properties than uncoated implants. The treat-ment of the implant surface played an important role on the stability of implants. The activity of osteoblasts increased when the surface was laser-treated followed by coating with chitosan. The subsequent coating with apatite improved the bioactivity of chitosan. Conclusion: Chitosan is a promising biocompatible and bioactive material in dental implantology. Its antibac-terial properties can be enhanced by modification of its structure. Its bioactive properties can be improved when mixing with hydroxy apatite. (c) 2022 Elsevier Masson SAS. All rights reserved.