Synbiotics for Improved Human Health: Recent Developments, Challenges, and Opportunities

被引：44
作者：
Krumbeck, Janina A. [1 ]
Walter, Jens [2 ,3 ]
Hutkins, Robert W. [4 ]
机构：
[1] Univ Nebraska, Sch Biol Sci, Lincoln, NE 68588 USA
[2] Univ Alberta, Dept Biol Sci, Edmonton, AB T6G 2R3, Canada
[3] Univ Alberta, Dept Agr Food & Nutr Sci, Edmonton, AB T6G 2P5, Canada
[4] Univ Nebraska, Dept Food Sci & Technol, Lincoln, NE 68588 USA
来源：
ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 9 | 2018年 / 9卷
关键词：
gut health; prebiotics; probiotics; synbiotics; CHAIN FATTY-ACIDS; IRRITABLE-BOWEL-SYNDROME; PROBIOTICS LACTOBACILLUS-RHAMNOSUS; RANDOMIZED CONTROLLED-TRIALS; PROTEIN-COUPLED RECEPTOR; CHRONIC KIDNEY-DISEASE; DOUBLE-BLIND; GUT MICROBIOTA; ULCERATIVE-COLITIS; CLINICAL-TRIAL;
D O I：
10.1146/annurev-food-030117-012757
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
Research on combining pro- and prebiotics as synbiotics to enhance human and animal health has accelerated in the past 10 years, including many clinical trials that have assessed a diverse range of synbiotic formulations. In this review, we summarize these studies as well as the commercial applications of synbiotics that are available. In particular, we critically assess the claimed health benefits of synbiotic applications and the ecological and therapeutic factors to consider when designing synbiotics and discuss the implications of these concepts for future research in this field.
引用
收藏
页码：451 / 479
页数：29
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