Synbiotics for Improved Human Health: Recent Developments, Challenges, and Opportunities

被引：44
|
作者：
Krumbeck, Janina A. [1 ]
Walter, Jens [2 ,3 ]
Hutkins, Robert W. [4 ]
机构：
[1] Univ Nebraska, Sch Biol Sci, Lincoln, NE 68588 USA
[2] Univ Alberta, Dept Biol Sci, Edmonton, AB T6G 2R3, Canada
[3] Univ Alberta, Dept Agr Food & Nutr Sci, Edmonton, AB T6G 2P5, Canada
[4] Univ Nebraska, Dept Food Sci & Technol, Lincoln, NE 68588 USA
来源：
ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 9 | 2018年 / 9卷
关键词：
gut health; prebiotics; probiotics; synbiotics; CHAIN FATTY-ACIDS; IRRITABLE-BOWEL-SYNDROME; PROBIOTICS LACTOBACILLUS-RHAMNOSUS; RANDOMIZED CONTROLLED-TRIALS; PROTEIN-COUPLED RECEPTOR; CHRONIC KIDNEY-DISEASE; DOUBLE-BLIND; GUT MICROBIOTA; ULCERATIVE-COLITIS; CLINICAL-TRIAL;
D O I：
10.1146/annurev-food-030117-012757
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
Research on combining pro- and prebiotics as synbiotics to enhance human and animal health has accelerated in the past 10 years, including many clinical trials that have assessed a diverse range of synbiotic formulations. In this review, we summarize these studies as well as the commercial applications of synbiotics that are available. In particular, we critically assess the claimed health benefits of synbiotic applications and the ecological and therapeutic factors to consider when designing synbiotics and discuss the implications of these concepts for future research in this field.
引用
收藏
页码：451 / 479
页数：29
相关论文
共 50 条
  • [1] Designing synbiotics for improved human health
    Kearney, Sean M.
    Gibbons, Sean M.
    MICROBIAL BIOTECHNOLOGY, 2018, 11 (01): : 141 - 144
  • [2] Recent developments in antimicrobial growth promoters in chicken health: Opportunities and challenges
    Kalia, Vipin Chandra
    Shim, Woo Yong
    Patel, Sanjay Kumar Singh
    Gong, Chunjie
    Lee, Jung-Kul
    SCIENCE OF THE TOTAL ENVIRONMENT, 2022, 834
  • [3] Recent developments in forward osmosis: Opportunities and challenges
    Zhao, Shuaifei
    Zou, Linda
    Tang, Chuyang Y.
    Mulcahy, Dennis
    JOURNAL OF MEMBRANE SCIENCE, 2012, 396 : 1 - 21
  • [4] Recent Developments, Challenges and Opportunities in Targeting the KRAS Pathway
    Pothuganti, Manoj Kumar
    Mitra, Sayan
    Iyer, Pravin
    Gowda, Nagaraj
    LETTERS IN DRUG DESIGN & DISCOVERY, 2023, 20 (08) : 992 - 1004
  • [5] Pancreatic cancer research: challenges, opportunities, and recent developments
    Fernandez-Zapico, ME
    Kaczynski, JA
    Urrutia, R
    CURRENT OPINION IN GASTROENTEROLOGY, 2002, 18 (05) : 563 - 567
  • [6] An overview of polyolefin foams - Opportunities, challenges and recent developments
    Park, CP
    FOAMS '99: FIRST INTERNATIONAL CONFERENCE ON THERMOPLASTIC FOAM, 1999, : 61 - 72
  • [7] Recent developments of the mainstream anammox processes: Challenges and opportunities
    Hoang Phuc Trinh
    Lee, Sang-Hoon
    Jeong, Garam
    Yoon, Hyeokjun
    Park, Hee-Deung
    JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, 2021, 9 (04):
  • [8] Plant Protein Structuring: Recent Developments, Opportunities, and Challenges
    Don, Clyde
    van der Goot, Atze Jan
    CEREAL FOODS WORLD, 2020, 65 (04)
  • [9] Recent developments, opportunities, and challenges in the study of mRNA pseudouridylation
    Gilbert, Wendy V.
    RNA, 2024, 30 (05) : 530 - 536
  • [10] Synthetic and medicinal chemistry of phthalazines: Recent developments, opportunities and challenges
    Zaib, Sumera
    Khan, Imtiaz
    BIOORGANIC CHEMISTRY, 2020, 105
12345