Human Pulmonary Hyperpolarized 129Xe MRI: a Preliminary Study

被引：0
|
作者：
Yang, Hao [1 ]
Wang, Ke [1 ]
Zhang, Hui-Ting [2 ]
Xie, Jun-Shuai [2 ]
Wu, Guang-Yao [1 ]
Zhou, Xin [2 ]
机构：
[1] Wuhan Univ, Zhongnan Hosp, Dept Radiol, Wuhan 430071, Hubei, Peoples R China
[2] Chinese Acad Sci, Wuhan Inst Phys & Math, Natl Ctr Magnet Resonance Wuhan, State Key Lab Magnet Resonance & Atom & Mol Phys, Wuhan 430071, Hubei, Peoples R China
来源：
CHINESE PHYSICS LETTERS | 2018年 / 35卷 / 05期
基金：
中国国家自然科学基金;
关键词：
COMPUTED-TOMOGRAPHY; MAGNETIC-RESONANCE; HEALTHY-VOLUNTEERS; DISEASE; LUNG; COPD; SMOKERS; ASTHMA; HE-3;
D O I：
10.1088/0256-307X/35/5/058701
中图分类号：
O4 [物理学];
学科分类号：
0702 ;
摘要：
We study the feasibility and safety of human lung hyperpolarized (HP) (129) Xe magnetic resonance imaging (MRI). There is no significant change in physiological parameters before and after the examinations of all subjects. Compared with computed tomography, HP (129) Xe MRI is sensitive to earlier and smaller ventilation defects. The distribution of the HP Xe-129 MRI signal reflects the pulmonary compliance with the gravity gradient. This is the first application of HP Xe-129 MRI ventilation imaging in China, and this technology is expected to provide more useful information for clinical practice.
引用
收藏
页数：4
相关论文
共 50 条
  • [21] Reproducibility of Hyperpolarized 129Xe MRI Ventilation Defect Percent in Severe Asthma to Evaluate Clinical Trial Feasibility
    Svenningsen, Sarah
    McIntosh, Marrissa
    Ouriadov, Alexei
    Matheson, Alexander M.
    Konyer, Norman B.
    Eddy, Rachel L.
    McCormack, David G.
    Noseworthy, Michael D.
    Nair, Parameswaran
    Parraga, Grace
    ACADEMIC RADIOLOGY, 2021, 28 (06) : 817 - 826
  • [22] Rapid pulmonary 129Xe ventilation MRI of discharged COVID-19 patients with zigzag sampling
    Fang, Yuan
    Li, Haidong
    Shen, Luyang
    Zhang, Ming
    Luo, Ming
    Li, Hongchuang
    Rao, Qiuchen
    Chen, Qi
    Li, Yecheng
    Li, Zimeng
    Zhao, Xiuchao
    Shi, Lei
    Zhou, Qian
    Han, Yeqing
    Guo, Fumin
    Zhou, Xin
    MAGNETIC RESONANCE IN MEDICINE, 2024, 92 (03) : 956 - 966
  • [23] Translational applications of hyperpolarized 3He and 129Xe
    Walkup, Laura L.
    Woods, Jason C.
    NMR IN BIOMEDICINE, 2014, 27 (12) : 1429 - 1438
  • [24] Regional fractional ventilation mapping in spontaneously breathing mice using hyperpolarized 129Xe MRI
    Imai, Hirohiko
    Matsumoto, Hironobu
    Miyakoshi, Erika
    Okumura, Shintaro
    Fujiwara, Hideaki
    Kimura, Atsuomi
    NMR IN BIOMEDICINE, 2015, 28 (01) : 24 - 29
  • [25] Review of Hyperpolarized Pulmonary Functional 129Xe MR for Long-COVID
    Wild, Jim M.
    Gleeson, Fergus V.
    Svenningsen, Sarah
    Grist, James T.
    Saunders, Laura C.
    Collier, Guilhem J.
    Sharma, Maksym
    Tcherner, Sam
    Mozaffaripour, Ali
    Matheson, Alexander M.
    Parraga, Grace
    JOURNAL OF MAGNETIC RESONANCE IMAGING, 2024, 59 (04) : 1120 - 1134
  • [26] Using hyperpolarized 129Xe MRI to quantify regional gas transfer in idiopathic pulmonary fibrosis
    Wang, Jennifer M.
    Robertson, Scott H.
    Wang, Ziyi
    He, Mu
    Virgincar, Rohan S.
    Schrank, Geoffry M.
    Smigla, Rose Marie
    O'Riordan, Thomas G.
    Sundy, John
    Ebner, Lukas
    Rackley, Craig R.
    McAdams, Page
    Driehuys, Bastiaan
    THORAX, 2018, 73 (01) : 21 - 28
  • [27] Repeatability of regional pulmonary functional metrics of Hyperpolarized 129Xe dissolved-phase MRI
    Hahn, Andrew D.
    Kammerman, Jeff
    Evans, Michael
    Zha, Wei
    Cadman, Robert, V
    Meyer, Keith
    Sandbo, Nathan
    Fain, Sean B.
    JOURNAL OF MAGNETIC RESONANCE IMAGING, 2019, 50 (04) : 1182 - 1190
  • [28] Single breath-hold measurement of pulmonary gas exchange and diffusion in humans with hyperpolarized 129Xe MR
    Xie, Junshuai
    Li, Haidong
    Zhang, Huiting
    Zhao, Xiuchao
    Shi, Lei
    Zhang, Ming
    Xiao, Sa
    Deng, He
    Wang, Ke
    Yang, Hao
    Sun, Xianping
    Wu, Guangyao
    Ye, Chaohui
    Zhou, Xin
    NMR IN BIOMEDICINE, 2019, 32 (05)
  • [29] Diffusion-Weighted Hyperpolarized 129Xe MRI in Healthy Volunteers and Subjects With Chronic Obstructive Pulmonary Disease
    Kaushik, S. Sivaram
    Cleveland, Zackary I.
    Cofer, Gary P.
    Metz, Gregory
    Beaver, Denise
    Nouls, John
    Kraft, Monica
    Auffermann, William
    Wolber, Jan
    McAdams, H. Page
    Driehuys, Bastiaan
    MAGNETIC RESONANCE IN MEDICINE, 2011, 65 (04) : 1155 - 1165
  • [30] Relaxation and exchange dynamics of hyperpolarized 129Xe in human blood
    Norquay, Graham
    Leung, General
    Stewart, Neil J.
    Tozer, Gillian M.
    Wolber, Jan
    Wild, Jim M.
    MAGNETIC RESONANCE IN MEDICINE, 2015, 74 (02) : 303 - 311
12345