A mild and facile method for one pot synthesis of 2,5-di-substituted 1,3,4-oxadiazoles at room temperature

被引：15

作者：

Rostamizadeh, Shahnaz ^{[1
]}

Ghamkhar, Somaye ^{[1
]}

机构：

[1] KN Toosi Univ Technol, Dept Chem, Tehran, Iran

来源：

CHINESE CHEMICAL LETTERS | 2008年 / 19卷 / 06期

关键词：

1,3,4-Oxadiazole; Acid hydrazide; Acyl halide; Phosphorus pentoxide;

D O I：

10.1016/j.cclet.2008.03.027

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

2,5-Di-substituted 1,3,4-oxadiazoles 3a-n have been synthesized as a one pot procedure from the reaction of acid hydrazide 1, acyl halides 2 and phosphorus pentoxide in acetonitrile at room temperature. High yield, short reaction time (10-15 min), mild condition, and easy work-up are advantages of this methodology. (C) 2008 Shahnaz Rostamizadeh. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

引用

收藏

页码：639 / 642

页数：4

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