Rethinking "Enterotypes"

被引：287

作者：

Knights, Dan ^{[1
,2
]}

Ward, Tonya L. ^{[2
]}

McKinlay, Christopher E. ^{[1
,2
]}

Miller, Hannah ^{[1
]}

Gonzalez, Antonio ^{[3
]}

McDonald, Daniel ^{[3
]}

Knight, Rob ^{[3
,4
,5
,6
]}

机构：

[1] Univ Minnesota, Dept Comp Sci & Engn, St Paul, MN 55108 USA

[2] Univ Minnesota, Inst Biotechnol, St Paul, MN 55108 USA

[3] Univ Colorado, Biofrontiers Inst, Boulder, CO 80309 USA

[4] Univ Colorado, Dept Chem & Biochem, Boulder, CO 80309 USA

[5] Univ Colorado, Dept Comp Sci, Boulder, CO 80309 USA

[6] Univ Colorado, Howard Hughes Med Inst, Boulder, CO 80309 USA

来源：

CELL HOST & MICROBE | 2014年 / 16卷 / 04期

关键词：

HUMAN GUT MICROBIOME;

D O I：

10.1016/j.chom.2014.09.013

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Classification of the human gut microbiome into distinct types, or "enterotypes,'' provides an attractive framework for understanding microbial variation in health and disease. However, as discussed here, several different methods of collapsing enterotype variation into a few discrete clusters suggest that enterotype distribution is continuous and can vary widely within an individual.

引用

页码：433 / 437

页数：5

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