Hypervalent iodine oxidation of benzil-α-arylimino oximes:: an efficient synthesis of 2,3-diphenylquinoxaline-1-oxides

被引：25

作者：

Aggarwal, Ranjana ^{[1
]}

Sumran, Garima ^{[1
]}

Saini, Anil ^{[1
]}

Singh, Shiv P. ^{[1
]}

机构：

[1] Kurukshetra Univ, Dept Chem, Kurukshetra 136119, Haryana, India

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 28期

关键词：

hypervalent iodine; iodobenzene diacetate; oxidative cyclization; benzil-alpha-arylimino oximes; 2,3-diphenylquinoxaline-1-oxides;

D O I：

10.1016/j.tetlet.2006.04.086

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A mild and efficient synthetic protocol for the oxidation of benzil-alpha-arylimino oximes 3 utilizing iodobenzene diacetate (IBD) as an oxidizing agent has been developed. Oximes 3, obtained by the condensation of (E)-benzil monoxime 2 with various appropriately substituted anilines 1, on treatment with iodobenzene diacetate in dichloromethane at room temperature underwent oxidative cyclization to afford 2,3-diphenylquinoxaline-1-oxide 4 in excellent yields. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：4969 / 4971

页数：3

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