Frontal brain activation in premature infants' response to auditory stimuli in neonatal intensive care unit

被引：34

作者：

Saito, Yuri ^{[1
]}

Fukuhara, Rie ^{[2
]}

Aoyama, Shiori ^{[3
]}

Toshima, Tamotsu ^{[4
]}

机构：

[1] Tokai Gakuin Univ, Dept Psychol, Gifu 5048511, Japan

[2] Hiroshima Prefectural Hosp, Hiroshima, Japan

[3] Hiroshima Univ, Hiroshima 730, Japan

[4] Prefectural Univ Hiroshima, Hiroshima, Japan

来源：

EARLY HUMAN DEVELOPMENT | 2009年 / 85卷 / 07期

基金：

日本学术振兴会;

关键词：

NIRS; NICU; Premature infant; Frontal brain; Auditory stimulus; NEAR-INFRARED SPECTROSCOPY; CHILDHOOD; BEHAVIOR; CORTISOL; RISK;

D O I：

10.1016/j.earlhumdev.2009.04.004

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The present study was focusing on the very few contacts with the mother's voice that NICU infants have in the womb as well as after birth, we examined whether they can discriminate between their mothers' utterances and those of female nurses in terms of the emotional bonding that is facilitated by prosodic utterances. Twenty-six premature infants were included in this study, and their cerebral blood flows were measured by near-infrared spectroscopy. They were exposed to auditory stimuli in the form of utterances made by their mothers and female nurses. A two (stimulus: mother and nurse) x two (recording site: right frontal area and left frontal area) analysis of variance (ANOVA) for these relative oxy-Hb values was conducted. The ANOVA showed a significant interaction between stimulus and recording site. The mother's and the nurse's voices were activated in the same way in the left frontal area, but showed different reactions in the right frontal area. We presume that the nurse's voice might become associated with pain and stress for premature infants. Our results showed that the premature infants reacted differently to the different voice stimuli. Therefore, we presume that both mothers' and nurses' voices represent positive stimuli for premature infants because both activate the frontal brain. Accordingly, we cannot explain our results only in terms of the state-dependent marker for infantile individual differences, but must also address the stressful trigger of nurses' voices for NICU infants. (C) 2009 Elsevier Ireland Ltd. All rights reserved.

引用

页码：471 / 474

页数：4

共 24 条

[1] Near-infrared spectroscopy for functional studies of brain activity in human infants: promise, prospects, and challenges [J].