DNA nanotechnology for building artificial dynamic systems

被引:6
作者
Liu, Na [1 ,2 ]
机构
[1] Heidelberg Univ, Max Planck Inst Intelligent Syst, Heidelberg, Germany
[2] Heidelberg Univ, Kirchhoff Inst Phys, Heidelberg, Germany
基金
欧洲研究理事会;
关键词
biological; biomimetic (assembly); nanostructure; chemical synthesis; devices; SUBUNIT ROTATION; KINESIN; MOTOR; MICROTUBULES; MECHANICS; MOVEMENT; PROTEINS;
D O I
10.1557/mrs.2019.155
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
A fundamental design rule that nature has developed for biological machines is the intimate correlation between motion and function. One class of biological machines is molecular motors in living cells, which directly convert chemical energy into mechanical work. They coexist in every eukaryotic cell, but differ in their types of motion, the filaments they bind to, the cargos they carry, as well as the work they perform. Such natural structures offer inspiration and blueprints for constructing DNA-assembled artificial systems, which mimic their functionality. In this article, we describe two groups of cytoskeletal motors, linear and rotary motors. We discuss how their artificial analogues can be built using DNA nanotechnology. Finally, we summarize ongoing research directions and conclude that DNA origami has a bright future ahead.
引用
收藏
页码:576 / 581
页数:6
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