A Review of Pickering Emulsions: Perspectives and Applications

被引:82
|
作者
Brito de Carvalho-Guimaraes, Fernanda [1 ]
Correa, Kamila Leal [1 ]
de Souza, Tatiane Pereira [2 ]
Rodriguez Amado, Jesus Rafael [3 ]
Ribeiro-Costa, Roseane Maria [4 ]
Silva-Junior, Jose Otavio Carrera [1 ]
机构
[1] Fed Univ Para, Coll Pharm, Lab Pharmaceut & Cosmet R&D, BR-66075110 Belem, Para, Brazil
[2] Univ Fed Amazonas, Fac Pharmaceut Sci, Lab Innovat & Dev Pharmaceut Technol, BR-69077000 Manaus, Amazonas, Brazil
[3] Univ Fed Mato Grosso do Sul, Fac Pharm Food & Nutr, Lab Pharmaceut Technol, BR-79070900 Campo Grande, MS, Brazil
[4] Fed Univ Para, Coll Pharm, Lab Pharmaceut Nanotechnol, BR-66075110 Belem, Para, Brazil
关键词
Pickering emulsion; solid particles; application; BACTERIAL CELLULOSE; CLAY-MINERALS; IN-VITRO; BIOMEDICAL APPLICATIONS; RHEOLOGICAL PROPERTIES; STABILIZED EMULSIONS; SILICA NANOPARTICLES; JANUS NANOPARTICLES; LAPONITE CLAY; PARTICLE-SIZE;
D O I
10.3390/ph15111413
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Pickering emulsions are systems composed of two immiscible fluids stabilized by organic or inorganic solid particles. These solid particles of certain dimensions (micro- or nano-particles), and desired wettability, have been shown to be an alternative to conventional emulsifiers. The use of biodegradable and biocompatible stabilizers of natural origin, such as clay minerals, presents a promising future for the development of Pickering emulsions and, with this, they deliver some advantages, especially in the area of biomedicine. In this review, the effects and characteristics of microparticles in the preparation and properties of Pickering emulsions are presented. The objective of this review is to provide a theoretical basis for a broader type of emulsion, in addition to reviewing the main aspects related to the mechanisms and applications to promote its stability. Through this review, we highlight the use of this type of emulsion and its excellent properties as permeability promoters of solid particles, providing ideal results for local drug delivery and use in Pickering emulsions.
引用
收藏
页数:21
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