Clonal haematopoiesis induces a pro-inflammatory monocyte phenotype in HF

被引:2
作者
Lim, Gregory B.
机构
[1] Nature Reviews Cardiology,
关键词
D O I
10.1038/s41569-020-00481-5
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In patients with heart failure who are carriers of a clonal haematopoiesis driver mutation in DNMT3A, circulating monocytes have a pro-inflammatory transcriptome, which might worsen disease progression.
引用
收藏
页码:74 / 74
页数:1
相关论文
共 3 条
[1]  
Abplanalp WT(2020)Clonal hematopoiesis-driver DNMT3A mutations alter immune cells in heart failure Circ. Res. 17 137-144
[2]  
Jaiswal S(2020)Clonal haematopoiesis: connecting ageing and inflammation in cardiovascular disease Nat. Rev. Cardiol. undefined undefined-undefined
[3]  
Libby P(undefined)undefined undefined undefined undefined-undefined