Surface antigen changes during normal neutrophilic development: A critical review

被引:172
作者
Elghetany, MT [1 ]
机构
[1] Univ Texas, Med Branch, Dept Pathol, Div Histopathol, Galveston, TX 77555 USA
关键词
D O I
10.1006/bcmd.2002.0513
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Neutrophil surface molecules function in part as biological sensors. Surface antigens undergo several changes during neutrophilic maturation to accommodate the cell's function. Surface antigens may appear with neutrophilic maturation, such as CD16b, CD35, and CD10; disappear with maturation, such as CD49d and CD64; be maintained during maturation, such as CD32, CD59, and CD82; or disappear with maturation but reappear after neutrophilic extravasation, such as CD49b. This article reviews the alterations in surface antigen expression during normal neutrophilic granulopoiesis. (C) 2002 Elsevier Science (USA).
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页码:260 / 274
页数:15
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