Highly selective detection of Cu2+ based on a thiosemicarbazone triphenylacetylene fluorophore

被引：13

作者：

Boontom, Sunisa ^{[1
,2
]}

Boonkitpatarakul, Kanokthorn ^{[3
,4
]}

Sukwattanasinitt, Mongkol ^{[3
,4
]}

Niamnont, Nakorn ^{[1
,2
]}

机构：

[1] King Mongkuts Univ Technol Thonburi, Fac Sci, Dept Chem, Organ Synth Electrochem & Nat Prod Res Unit, Bangkok 10140, Thailand

[2] King Mongkuts Univ Technol Thonburi, Fac Sci, Luminescence & Scintillat Mat Res Unit, Bangkok 10140, Thailand

[3] Chulalongkorn Univ, Dept Chem, Fac Sci, Bangkok 10330, Thailand

[4] Chulalongkorn Univ, NanotecCU Ctr Excellence Food & Agr, Bangkok 10330, Thailand

来源：

TETRAHEDRON | 2017年 / 73卷 / 17期

关键词：

Baker's yeast; Copper(II); Fluorescent probe; Thiosemicarbazone; FLUORESCENT SENSOR; DUAL CHEMOSENSOR; VISUAL DETECTION; MOLECULAR-BASIS; METAL-IONS; COPPER; RECOGNITION; SENSITIVITY; CU(II); FE3+;

D O I：

10.1016/j.tet.2017.03.044

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel thiosemicarbazone fluorophore (3) was successfully synthesized in 3 steps via Sonogashira coupling and Knoevenagel condensation using baker's yeast (Saccharomyces cerevisiae) as a biocatalyst. Compound 3 contains triphenylacetylene, which acts as a fluorophore, and thiosemicarbazone, which acts as a copper probe. Compound 3 exhibited highly selective detection of Cu2+ ions based on photo-induced electron transfer (PET) in 10 mM HEPES buffer pH 7.4/propylene glycol (70% (v/v)). A linear relationship was observed for Cu2+ concentrations between 0.1 nM and 10 mu M, and the detection limit of the method was 0.14 nM. Additionally, 3 was utilized to detect Cu2+ in wastewater with satisfactory results, which highlighted its potential for real sample applications. (C) 2017 Elsevier Ltd. All rights reserved.

引用

页码：2483 / 2487

页数：5

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