Significance of Chalcone Synthons as Lead Molecules in Anticancer Drug Discovery

[1] Novel Aryl-Substituted Pyrimidones as Inhibitors of 3-Mercaptopyruvate Sulfurtransferase with Antiproliferative Efficacy in Colon Cancer [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2021, 64 (09) : 6221 - 6240

[2] Design, Synthesis, and Preclinical Evaluation of Fused Pyrimidine-Based Hydroxamates for the Treatment of Hepatocellular Carcinoma [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2018, 61 (04) : 1552 - 1575

[3] Anticancer cyclometalated complexes of platinum group metals and gold [J]. COORDINATION CHEMISTRY REVIEWS, 2013, 257 (19-20) : 2784 - 2797

[4] Anticancer Active Heterocyclic Chalcones: Recent Developments [J]. ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2021, 21 (05) : 558 - 566

[5] Henry N.L., 2020, ABELOFFS CLIN ONCOLO, V6th, DOI [10.1016/B978-0-323-47674-4.00088-8, DOI 10.1016/B978-0-323-47674-4.00088-8]

[6] Anticancer activities of chalcone flavokawain B from Alpinia pricei Hayata in human lung adenocarcinoma (A549) cells via induction of reactive oxygen species-mediated apoptotic and autophagic cell death [J]. JOURNAL OF CELLULAR PHYSIOLOGY, 2019, 234 (10) : 17514 - 17526

[7] Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2018, 61 (19) : 8754 - 8773

[8] Synthesis, Molecular Docking and Biological Activity Evaluation of Alkoxy Substituted Chalcone Derivatives: Potential Apoptosis Inducing Agent on MCF-7 Cells [J]. ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2021, 21 (13) : 1738 - 1750

[9] Molecular Mechanisms of Antiproliferative Effects of Natural Chalcones [J]. CANCERS, 2021, 13 (11)

[10] Chalcones as Promising Antitumor Agents by Targeting the p53 Pathway: An Overview and New Insights in Drug-Likeness [J]. MOLECULES, 2021, 26 (12):

[1] Novel Aryl-Substituted Pyrimidones as Inhibitors of 3-Mercaptopyruvate Sulfurtransferase with Antiproliferative Efficacy in Colon Cancer [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2021, 64 (09) : 6221 - 6240

[2] Design, Synthesis, and Preclinical Evaluation of Fused Pyrimidine-Based Hydroxamates for the Treatment of Hepatocellular Carcinoma [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2018, 61 (04) : 1552 - 1575

[3] Anticancer cyclometalated complexes of platinum group metals and gold [J]. COORDINATION CHEMISTRY REVIEWS, 2013, 257 (19-20) : 2784 - 2797

[4] Anticancer Active Heterocyclic Chalcones: Recent Developments [J]. ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2021, 21 (05) : 558 - 566

[5] Henry N.L., 2020, ABELOFFS CLIN ONCOLO, V6th, DOI [10.1016/B978-0-323-47674-4.00088-8, DOI 10.1016/B978-0-323-47674-4.00088-8]

[6] Anticancer activities of chalcone flavokawain B from Alpinia pricei Hayata in human lung adenocarcinoma (A549) cells via induction of reactive oxygen species-mediated apoptotic and autophagic cell death [J]. JOURNAL OF CELLULAR PHYSIOLOGY, 2019, 234 (10) : 17514 - 17526

[7] Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2018, 61 (19) : 8754 - 8773

[8] Synthesis, Molecular Docking and Biological Activity Evaluation of Alkoxy Substituted Chalcone Derivatives: Potential Apoptosis Inducing Agent on MCF-7 Cells [J]. ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2021, 21 (13) : 1738 - 1750

[9] Molecular Mechanisms of Antiproliferative Effects of Natural Chalcones [J]. CANCERS, 2021, 13 (11)

[10] Chalcones as Promising Antitumor Agents by Targeting the p53 Pathway: An Overview and New Insights in Drug-Likeness [J]. MOLECULES, 2021, 26 (12):