Toying with memory in the hippocampus

被引:15
作者
Eichenbaum, H
Harris, K
机构
[1] Boston Univ, Dept Psychol, Boston, MA 02215 USA
[2] Boston Univ, Dept Biol, Boston, MA 02215 USA
关键词
D O I
10.1038/72901
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Mice lacking NMDA receptors in hippocampal area CA1 are deficient in spatial memory. They also have nonspatial memory deficits, which are overcome by environmental enrichment.
引用
收藏
页码:205 / 206
页数:2
相关论文
共 15 条
[1]   Control of spine formation by electrical activity in the adult rat cerebellum [J].
Bravin, M ;
Morando, L ;
Vercelli, A ;
Rossi, F ;
Strata, P .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (04) :1704-1709
[2]   Declarative memory: Insights from cognitive neurobiology [J].
Eichenbaum, H .
ANNUAL REVIEW OF PSYCHOLOGY, 1997, 48 :547-572
[3]  
Hebb D, 1949, ORG BEHAV
[4]   DORSAL AND VENTRAL HIPPOCAMPUS LESIONS AND MAZE-LEARNING - INFLUENCE OF PREOPERATIVE ENVIRONMENT [J].
HUGHES, KR .
CANADIAN JOURNAL OF PSYCHOLOGY, 1965, 19 (04) :325-332
[5]  
James W., 1890, PRINCIPLES PSYCHOL, V2
[6]   Dendrites are more spiny on mature hippocampal neurons when synapses are inactivated [J].
Kirov, SA ;
Harris, KM .
NATURE NEUROSCIENCE, 1999, 2 (10) :878-883
[7]   Synaptic plasticity in cortical systems [J].
Klintsova, AY ;
Greenough, WT .
CURRENT OPINION IN NEUROBIOLOGY, 1999, 9 (02) :203-208
[8]   VDCCs and NMDARs underlie two forms of LTP in CA1 hippocampus in vivo [J].
Morgan, SL ;
Teyler, TJ .
JOURNAL OF NEUROPHYSIOLOGY, 1999, 82 (02) :736-740
[9]  
Muller D, 1997, REV NEUROSCIENCE, V8, P77
[10]   Enrichment induces structural changes and recovery from nonspatial memory deficits in CA1 NMDAR1-knockout mice [J].
Rampon, C ;
Tang, YP ;
Goodhouse, J ;
Shimizu, E ;
Kyin, M ;
Tsien, JZ .
NATURE NEUROSCIENCE, 2000, 3 (03) :238-244