Efficacy of a combined nanoparticulate/calcium hydroxide root canal medication on elimination of Enterococcus faecalis

被引：57

作者：

Javidi, Maryam ^{[1
]}

Afkhami, Farzaneh ^{[2
]}

Zarei, Mina ^{[1
]}

Ghazvini, Kiarash ^{[3
]}

Rajabi, Omid ^{[4
]}

机构：

[1] Mashhad Univ Med Sci, Dept Endodont, Mashhad, Iran

[2] Univ Tehran Med Sci, Dept Endodont, Tehran, Iran

[3] Mashhad Univ Med Sci, Fac Med, Microbiol Res Ctr, Mashhad, Iran

[4] Mashhad Univ Med Sci, Fac Pharm, Dept Pharmaceut Chem, Mashhad, Iran

来源：

AUSTRALIAN ENDODONTIC JOURNAL | 2014年 / 40卷 / 02期

关键词：

calcium hydroxide; Enterococcus faecalis; intracanal dressings; silver nanoparticles; VITRO ANTIMICROBIAL ACTIVITY; CALCIUM HYDROXIDE; IN-VITRO; DENTINAL TUBULES; 2-PERCENT CHLORHEXIDINE; SILVER NANOPARTICLES; CITRIC-ACID; DISINFECTION; MEDICAMENTS; MECHANISMS;

D O I：

10.1111/aej.12028

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

The purpose of this study was to evaluate the efficacy of Ca(OH)(2) with or without a silver nanoparticle suspension to eliminate Enterococcus faecalis from root canals. A total of 66 extracted human single-rooted teeth contaminated with E.faecalis were treated with 10% Ca(OH)(2) alone, Ca(OH)(2) with nanosilver or sterile water (as a negative control). Samples were obtained with paper points and Gates-Glidden burs at 1 and 7days after root canal preparation and the number of colony-forming units (CFU) was determined. The number of CFUs observed after dressing with Ca(OH)(2)+nanosilver was significantly less than the number observed with Ca(OH)(2) alone after 1 or 7days (P<0.001, P<0.001). No differences in antimicrobial properties were observed between the two time points in the Ca(OH)(2)+nanosilver group (P>0.05). Higher antimicrobial efficacy was observed in the Ca(OH)(2) group after 7days than 1day (P<0.001). This study highlighted the potential advantage of using a mixture of Ca(OH)(2) and nanosilver for intracanal medicament.

引用

页码：61 / 65

页数：5

共 28 条

[1] Bactericidal activity of phosphoric acid, citric acid, and EDTA solutions against Enterococcus faecalis [J].