Translational vitreous proteomics

被引:34
作者
Mahajan, Vinit B. [1 ,2 ]
Skeie, Jessica M. [1 ,2 ]
机构
[1] Univ Iowa, Dept Ophthalmol & Visual Sci, Iowa City, IA 52242 USA
[2] Univ Iowa, Omics Lab, Iowa City, IA 52242 USA
关键词
Retina; Vitrectomy; Vitreoretinopathy; Vitreous; PROLIFERATIVE DIABETIC-RETINOPATHY; FLUOCINOLONE ACETONIDE IMPLANT; AUTOIMMUNE UVEITIS; INHIBITORY FACTOR; EYES; RANIBIZUMAB; MEMBRANE; PROTEINS; REVEALS; TISSUE;
D O I
10.1002/prca.201300062
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The vitreous is an extracellular matrix that is still poorly understood. Although many constituents and characteristics have been previously determined, there are many attributes still being discovered. Currently, using protein arrays, MS, and bioinformatics, the vitreous provides a wealth of knowledge regarding ocular diseases and potential targets for personalized therapeutics.
引用
收藏
页码:204 / 208
页数:5
相关论文
共 44 条
[41]   Comprehensive Analysis of Inflammatory Immune Mediators in Vitreoretinal Diseases [J].
Yoshimura, Takeru ;
Sonoda, Koh-Hei ;
Sugahara, Mika ;
Mochizuki, Yasutaka ;
Enaida, Hiroshi ;
Oshima, Yuji ;
Ueno, Akifumi ;
Hata, Yasuaki ;
Yoshida, Hiroki ;
Ishibashi, Tatsuro .
PLOS ONE, 2009, 4 (12)
[42]   Vitreous proteomic analysis of proliferative vitreoretinopathy [J].
Yu, Jing ;
Liu, Feng ;
Cui, Shu-Jian ;
Liu, Yan ;
Song, Zheng-Yu ;
Cao, Hui ;
Chen, Feng-E ;
Wang, Wei-Jun ;
Sun, Tao ;
Wang, Fang .
PROTEOMICS, 2008, 8 (17) :3667-3678
[43]   An investigation into the human serum "interactome" [J].
Zhou, M ;
Lucas, DA ;
Chan, KC ;
Issaq, HJ ;
Petricoin, EF ;
Liotta, LA ;
Veenstra, TD ;
Conrads, TR .
ELECTROPHORESIS, 2004, 25 (09) :1289-1298
[44]  
Zhou Ru, 2010, F1000 Biol Rep, V2, DOI 10.3410/B2-3