Risk factors for recurrent nerve palsy after thyroid surgery: a national study of patients treated at Danish departments of ENT Head and Neck Surgery

被引：57

作者：

Godballe, Christian ^{[1
]}

Madsen, Anders Rorbaek ^{[1
]}

Sorensen, Christian Hjort ^{[2
]}

Schytte, Sten ^{[3
]}

Trolle, Waldemar ^{[4
]}

Helweg-Larsen, Jens ^{[5
]}

Barfoed, Lisa ^{[6
]}

Kristiansen, Larry ^{[7
]}

Sorensen, Vibeke Zederkof ^{[8
]}

Samuelsen, Grethe ^{[9
]}

Pedersen, Henrik Baymler ^{[10
]}

机构：

[1] Odense Univ Hosp, Dept ENT Head & Neck Surg, DK-5000 Odense C, Denmark

[2] Gentofte Univ Hosp, Dept ENT Head & Neck Surg, Hellerup, Denmark

[3] Aarhus Univ Hosp, Dept ENT Head & Neck Surg, DK-8000 Aarhus, Denmark

[4] Copenhagen Univ Hosp, Rigshosp, Dept ENT Head & Neck Surg, Copenhagen, Denmark

[5] Vejle Hosp, Dept ENT Head & Neck Surg, Vejle, Denmark

[6] Slagelse Hosp, Dept ENT Head & Neck Surg, Slagelse, Denmark

[7] Viborg Hosp, Dept ENT Head & Neck Surg, Viborg, Denmark

[8] Koge Hosp, Dept ENT Head & Neck Surg, Koge, Denmark

[9] Hillerod Hosp, Dept ENT Head & Neck Surg, Hillerod, Denmark

[10] Aalborg Univ Hosp, Dept ENT Head & Neck Surg, Aalborg, Denmark

来源：

EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY | 2014年 / 271卷 / 08期

关键词：

Thyroid surgery; Recurrent nerve palsy; Risk factors; National study; LARYNGEAL NERVE; PARATHYROID SURGERY; COMPLICATIONS; MULTICENTER; TRENDS;

D O I：

10.1007/s00405-013-2767-7

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

Recurrent laryngeal nerve (RLN) injury is a well-known and serious complication to thyroid surgery. The objective was to estimate the frequency of post-thyroidectomy RLN palsy and to identify possible risk factors. Based on the Danish national thyroid surgery database, 6,859 patients treated with thyroid surgery from 1 January 2001 to the 31 December 2008 at the Danish departments of ENT-HNS were analyzed. Unilateral RLN palsy was found in 2.1 % and bilateral in 0.1 %. In benign histology, RLN palsies were registered in 1.3 %. Malignant histology and accordingly neck dissection were the most predominant risk factors with a relative risk (RR) of 5.4 and 5.8, respectively. In benign cases previous performed thyroid surgery had a RR of 10.4. High volume departments with more than 150 thyroid procedures per year seem to perform significantly better. Malignant histology, neck dissection and previous performed thyroid surgery are the strongest predictors for RLN palsy and patient information should be given accordingly. Incomplete resections should be reserved for isthmectomy only. Centralization of thyroid surgery in larger units might improve quality.

引用

页码：2267 / 2276

页数：10

共 19 条

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