Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Febrile Neonates

被引：33

作者：

Wardell, Hanna ^{[1
,2
]}

Campbell, Jeffrey, I ^{[1
,2
]}

VanderPluym, Christina ^{[2
,3
]}

Dixit, Avika ^{[1
]}

机构：

[1] Boston Childrens Hosp, Dept Pediat, Div Infect Dis, 300 Longwood Ave, Boston, MA 02115 USA

[2] Harvard Med Sch, Boston, MA 02115 USA

[3] Boston Childrens Hosp, Dept Cardiol, Boston, MA 02115 USA

来源：

JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY | 2020年 / 9卷 / 05期

关键词：

COVID-19; infant; neonatal sepsis; remdesivir; SARS-CoV-2; INFANTS;

D O I：

10.1093/jpids/piaa084

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Most severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in pediatric patients are mild or asymptomatic. However, infants have emerged at higher risk of hospitalization and severe outcomes in pediatric coronavirus disease 2019 (COVID-19). We report a case series of 4 full-term neonates hospitalized with fever and found to have SARS-CoV-2 infection with a spectrum of illness severities. Two neonates required admission to the intensive care unit for respiratory insufficiency and end organ involvement. Half of the patients were found to have a coinfection. One neonate received antiviral therapy with remdesivir and is, to our knowledge, the youngest patient to receive this drug for COVID-19. All neonates had favorable outcomes.

引用

页码：630 / 635

页数：6

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