"Chronic Disseminated Aspergillosis," a Novel Fungal Immune Reconstitution Inflammatory Syndrome

被引：3

作者：

Pourbaix, Annabelle ^{[1
]}

Guery, Romain ^{[1
]}

Bruneau, Julie ^{[2
]}

Blanc, Estelle ^{[3
]}

Jouvion, Gregory ^{[4
,5
]}

Weinandt, Marthe ^{[6
]}

Rouzaud, Claire ^{[1
]}

Lourenco, Jeremy ^{[1
]}

Boutboul, David ^{[7
]}

Mira, Jean-Paul ^{[8
]}

Rouquette, Alexandre ^{[9
]}

Molina, Thierry Jo ^{[2
]}

Lecuit, Marc ^{[1
,10
]}

Lortholary, Olivier ^{[1
,11
]}

机构：

[1] Paris Univ, Necker Enfants Malad Hosp, AP HP, Infect Dis & Trop Med Dept, Paris, France

[2] Paris Descartes Univ, Necker Enfants Malad Hosp, AP HP, Pathol Dept, Paris, France

[3] Marie Lannelongue Hosp, Nucl Med Dept, Le Plessis Robinson, France

[4] Sorbonne Univ, Hop Armand Trousseau, AP HP, UF Genet Mol,Pathophysiol Pediat Genet Dis,INSERM, Paris, France

[5] Inst Pasteur, Expt Neuropathol Unit, Paris, France

[6] Paris Descartes Univ, Cochin Hosp, AP HP, Visceral Surg Dept, Paris, France

[7] Univ Paris, St Louis Hosp, AP HP, Clin Immunopathol Dept,INSERM U967,HIPI, Paris, France

[8] Paris Descartes Univ, Cochin Hosp, AP HP, Med Intens Care Dept, Paris, France

[9] Paris Descartes Univ, Cochin Hosp, AP HP, Pathol Dept, Paris, France

[10] Inst Pasteur, Biol Infect Unit, INSERM U1117, Paris, France

[11] Inst Pasteur, Mol Mycol Unit, CNRS UMR2000, Paris, France

来源：

OPEN FORUM INFECTIOUS DISEASES | 2020年 / 7卷 / 11期

关键词：

aspergillosis; hepatosplenic; immune reconstitution inflammatory syndrome;

D O I：

10.1093/ofid/ofaa175

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We report a case of chronic hepatosplenic aspergillosis following immune reconstitution complicating colic aspergillosis in an AIDS patient with multicentric Castleman disease. Symptoms mimicked the clinical presentation of chronic disseminated candidiasis and responded to corticosteroid. This emerging entity enlarges the spectrum of fungal immune reconstitution inflammatory syndrome in the HIV setting.

引用

页数：4

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