Results of ajmaline testing in patients with arrhythmogenic right ventricular dysplasia-cardiomyopathy

被引：47

作者：

Peters, S ^{[1
]}

Trümmel, M ^{[1
]}

Denecke, S ^{[1
]}

Koehler, B ^{[1
]}

机构：

[1] Univ Hosp Magdeburg, Acad Teaching Hosp, Dept Cardiol, Klinikum Dorothea Christiane Erxleben gGmbH Quedl, D-06484 Quedlinburg, Germany

来源：

INTERNATIONAL JOURNAL OF CARDIOLOGY | 2004年 / 95卷 / 2-3期

关键词：

ajmaline testing; Brugada phenomenon; arrhythmogenic right ventricular dysplasia-cardiomyopathy; EP study; ST segment elevation;

D O I：

10.1016/j.ijcard.2003.04.032

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

An association between arrhythmogenic right ventricular dysplasia-cardiomyopathy (ARVD/C) and Brugada syndrome can be supposed according to several case reports. In order to examine a possible link between ARVD/C and Brugada syndrome, systematic ajmaline testing with 1 mg/kg body weight intravenously, was done in 55 patients (32 males, mean age 46.7 +/- 12.3 years) with ISFC/ESC criteria of ARVD/C. In nine patients ajmaline testing could demonstrate coved ST segment elevation of at least 2 mm in at least two tight precordial leads. Three of these patients had recurrent syncopes. Electrophysiological study revealed non-sustained ventricular tachycardia with left bundle branch block configuration and inferior axis in only one case. Systematic ajmaline testing could demonstrate a definite link between ARVD/C and Brugada syndrome. (C) 2003 Elsevier Ireland Ltd. All rights reserved.

引用

页码：207 / 210

页数：4

共 19 条

[1] Localization of a gene responsible for arrhythmogenic right ventricular dysplasia to chromosome 3p23 [J].