Total synthesis of catenioblin B

被引：2

作者：

Srinivas, Theegala ^{[1
,2
]}

Huegel, Helmut M. ^{[1
,2
]}

Krishna, Palakodety Radha ^{[1
]}

机构：

[1] CSIR, Indian Inst Chem Technol, Organ & Biomol Chem Div, D211,Discovery Lab, Hyderabad 500007, Andhra Pradesh, India

[2] RMIT Univ, Sch Appl Sci, Melbourne, Vic 300, Australia

来源：

TETRAHEDRON LETTERS | 2014年 / 55卷 / 43期

关键词：

Catenioblins; Pyranone derivative; Sharpless epoxidation; Regioselective epoxide ring-opening; Grignard reaction; STEREOSELECTIVE TOTAL-SYNTHESIS; ENANTIOSELECTIVE PREPARATION; BUTYROLACTONES; LACTONES; ALCOHOLS; CORE;

D O I：

10.1016/j.tetlet.2014.09.034

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Herein we report the first total synthesis of catenioblin B (1) via a titanium(IV) mediated regioselective epoxide ring-opening, Grignard reaction, Luche's reduction and TEMPO/BAIB mediated intramolecular cyclization as the key steps. (C) 2014 Elsevier Ltd. All rights reserved.

引用

收藏

页码：5952 / 5954

页数：3

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