Vital Signs: Estimated Percentages and Numbers of Adults with Indications for Preexposure Prophylaxis to Prevent HIV Acquisition - United States, 2015

被引：294

作者：

Smith, Dawn K. ^{[1
]}

Van Handel, Michelle ^{[1
]}

Wolitski, Richard J. ^{[1
]}

Stryker, Jo Ellen ^{[1
]}

Hall, H. Irene ^{[1
]}

Prejean, Joseph ^{[1
]}

Koenig, Linda J. ^{[1
]}

Valleroy, Linda A. ^{[1
]}

机构：

[1] CDC, Div HIV AIDS Prevent, Natl Ctr HIV AIDS, Viral Hepatitis STD & TB Prevent, Atlanta, GA 30333 USA

来源：

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT | 2015年 / 64卷 / 46期

关键词：

ANTIRETROVIRAL PROPHYLAXIS; MEN;

D O I：

10.15585/mmwr.mm6446a4

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Background: In 2014, approximately 40,000 persons in the United States received a diagnosis of human immunodeficiency virus (HIV) infection. Preexposure prophylaxis (PrEP) with daily oral antiretroviral medication is a new, highly effective intervention that could reduce the number of new HIV infections. Methods: CDC analyzed nationally representative data to estimate the percentages and numbers of persons in the United States, by transmission risk group, with indications for PrEP consistent with the 2014 U.S. Public Health Service's PrEP clinical practice guideline. Results: Approximately 24.7% of sexually active adult men who have sex with men (MSM) (492,000 [95% confidence interval {CI} = 212,000-772,0001), 18.5% of persons who inject drugs (115,000 [CI = 45,000-185,000]), and 0.4% of heterosexually active adults (624,000 [CI = 404,000-846,000]), had substantial risks for acquiring HIV consistent with PrEP indications. Conclusions: Based on current guidelines, many MSM, persons who inject drugs, and heterosexually active adults have indications for PrEP. A higher percentage of MSM and persons who inject drugs have indications for PrEP than heterosexually active adults, consistent with distribution of new HIV diagnoses across these populations.

引用

页码：1291 / 1295

页数：5

共 19 条

[1]

[Anonymous], HIV SURV REP

[2]

[Anonymous], NAT HIV AIDS STRAT U

[3]

[Anonymous], 8 INT AIDS SOC C HIV

[4]

[Anonymous], 2015, NY TIMES

[5]

Baeten J., Near elimination of HIV transmission in a demonstration project of PrEP and ART

[6] Antiretroviral Prophylaxis for HIV Prevention in Heterosexual Men and Women [J].

Baeten, J. M. ;

Donnell, D. ;

Ndase, P. ;

Mugo, N. R. ;

Campbell, J. D. ;

Wangisi, J. ;

Tappero, J. W. ;

Bukusi, E. A. ;

Cohen, C. R. ;

Katabira, E. ;

Ronald, A. ;

Tumwesigye, E. ;

Were, E. ;

Fife, K. H. ;

Kiarie, J. ;

Farquhar, C. ;

John-Stewart, G. ;

Kakia, A. ;

Odoyo, J. ;

Mucunguzi, A. ;

Nakku-Joloba, E. ;

Twesigye, R. ;

Ngure, K. ;

Apaka, C. ;

Tamooh, H. ;

Gabona, F. ;

Mujugira, A. ;

Panteleeff, D. ;

Thomas, K. K. ;

Kidoguchi, L. ;

Krows, M. ;

Revall, J. ;

Morrison, S. ;

Haugen, H. ;

Emmanuel-Ogier, M. ;

Ondrejcek, L. ;

Coombs, R. W. ;

Frenkel, L. ;

Hendrix, C. ;

Bumpus, N. N. ;

Bangsberg, D. ;

Haberer, J. E. ;

Stevens, W. S. ;

Lingappa, J. R. ;

Celum, C. .

NEW ENGLAND JOURNAL OF MEDICINE, 2012, 367 (05) :399-410

[7]

CDC, 2015, HIV SURVEILLANCE S, P20

[8]

CDC, 2015, HIV FUND UPD

[9] Antiretroviral prophylaxis for HIV infection in injecting drug users in Bangkok, Thailand (the Bangkok Tenofovir Study): a randomised, double-blind, placebo-controlled phase 3 trial [J].

Choopanya, Kachit ;

Martin, Michael ;

Suntharasamai, Pravan ;

Sangkum, Udomsak ;

Mock, Philip A. ;

Leethochawalit, Manoj ;

Chiamwongpaet, Sithisat ;

Kitisin, Praphan ;

Natrujirote, Pitinan ;

Kittimunkong, Somyot ;

Chuachoowong, Rutt ;

Gvetadze, Roman J. ;

McNicholl, Janet M. ;

Paxton, Lynn A. ;

Curlin, Marcel E. ;

Hendrix, Craig W. ;

Vanichseni, Suphak .

LANCET, 2013, 381 (9883) :2083-2090

[10] Preexposure Chemoprophylaxis for HIV Prevention in Men Who Have Sex with Men. [J].

Grant, Robert M. ;

Lama, Javier R. ;

Anderson, Peter L. ;

McMahan, Vanessa ;

Liu, Albert Y. ;

Vargas, Lorena ;

Goicochea, Pedro ;

Casapia, Martin ;

Guanira-Carranza, Juan Vicente ;

Ramirez-Cardich, Maria E. ;

Montoya-Herrera, Orlando ;

Fernandez, Telmo ;

Veloso, Valdilea G. ;

Buchbinder, Susan P. ;

Chariyalertsak, Suwat ;

Schechter, Mauro ;

Bekker, Linda-Gail ;

Mayer, Kenneth H. ;

Kallas, Esper Georges ;

Amico, K. Rivet ;

Mulligan, Kathleen ;

Bushman, Lane R. ;

Hance, Robert J. ;

Ganoza, Carmela ;

Defechereux, Patricia ;

Postle, Brian ;

Wang, Furong ;

McConnell, J. Jeff ;

Zheng, Jia-Hua ;

Lee, Jeanny ;

Rooney, James F. ;

Jaffe, Howard S. ;

Martinez, Ana I. ;

Burns, David N. ;

Glidden, David V. .

NEW ENGLAND JOURNAL OF MEDICINE, 2010, 363 (27) :2587-2599

← 1 2 →