The Characterization of Antibiotic Resistance of Bacterial Isolates from Intensive Care Unit Patient Samples in a University Affiliated Hospital in Romania

被引:0
作者
Golli, Andreea-Loredana [1 ]
Nitu, Floarea Mimi [1 ]
Balasoiu, Maria [1 ]
Lungu, Marina Alina [2 ]
Dragomirescu, Cristiana Cerasella [3 ]
Olteanu, Madalina [1 ]
Nemes, Roxana Maria [4 ]
Tantu, Monica Marilena [5 ]
Olteanu, Mihai [1 ]
机构
[1] Univ Med & Pharm Craiova, 2 Petru Rares Str, Craiova, Romania
[2] Cty Emergency Clin Hosp Craiova, 1 Tabaci Str, Craiova, Romania
[3] Cantacuzino Natl Med Mil Res Dev Inst, Splaiul Independenei 103, Bucharest, Romania
[4] Titu Maiorescu Univ Bucharest, Fac Med, 22 Dambovnicului Str, Bucharest, Romania
[5] Univ Pitesti, Fac Sci Phys Educ & Informat, Med Assistance & Phys Therapy Dept, 1 Targu Din Vale Str, Pitesti 110040, Romania
来源
REVISTA DE CHIMIE | 2019年 / 70卷 / 05期
关键词
multidrug resistance (MDR); intensive care unit; bacterial pathogen; ANTIMICROBIAL RESISTANCE; MULTIDRUG-RESISTANT; SMOKING-CESSATION; TUBERCULOSIS; PATHOGENS; SURVEILLANCE; INFECTIONS; PATTERN; TRENDS;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
To determine the resistance pattern of bacterial pathogens involved in infections of the patients aged between 18-64 years, admitted in a ICU from a 1518-bed university-affiliated hospital. A retrospective study of bacterial pathogens was carried out on 351 patients aged between 18-64 years admitted to the ICU, from January to December 2017. In this study there were analysed 469 samples from 351 patients (18-64 years). A total of 566 bacterial isolates were obtained, of which 120 strains of Klebsiella spp. (35.39%%), followed by Nonfermenting Gram negative bacilli, other than Pseudomonas and Acinetobacter (NFB) (75- 22.12%), Acinetobacter spp. (53 - 15.63%), Pseudomonas aeruginosa and Proteus (51 - 15.04%), and Escherichia coli (49 - 14.45%). The most common isolates were from respiratory tract (394 isolates - 69.61%). High rates of MDR were found for Pseudomonas aeruginosa (64.70%), MRSA (62.65%) and Klebsiella spp. (53.33%), while almost all of the isolated NFB strains were MDR (97.33%). There was statistic difference between the drug resistance rate of Klebsiella and E. coli strains to ceftazidime and ceftriaxone (p<0.001), cefuroxime (p<0.01) and to cefepime (p<0.01). The study revealed an alarming pattern of antibiotic resistance in the majority of ICU isolates.
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页码:1778 / 1783
页数:6
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