High-intensity intermittent exercise attenuates ad-libitum energy intake

OBJECTIVE: To examine the acute effects of high-intensity intermittent exercise (HIIE) on energy intake, perceptions of appetite and appetite-related hormones in sedentary, overweight men. DESIGN: Seventeen overweight men (body mass index: 27.7 +/- 1.6 kg m(-2); body mass: 89.8 +/- 10.1 kg; body fat: 30.0 +/- 4.3%; VO2peak: 39.2 +/- 4.8 ml kg(-1) min(-1)) completed four 30-min experimental conditions using a randomised counterbalanced design. CON: resting control, MC: continuous moderate-intensity exercise (60% VO2peak), HI: high-intensity intermittent exercise (alternating 60 s at 100% VO2peak and 240 s at 50% VO2peak), VHI: very-high-intensity intermittent exercise (alternating 15 s at 170% VO2peak and 60 s at 32% VO2peak). Participants consumed a standard caloric meal following exercise/CON and an ad-libitum meal 70 min later. Capillary blood was sampled and perceived appetite assessed at regular time intervals throughout the session. Free-living energy intake and physical activity levels for the experimental day and the day after were also assessed. RESULTS: Ad-libitum energy intake was lower after HI and VHI compared with CON (P = 0.038 and P = 0.004, respectively), and VHI was also lower than MC (P = 0.028). Free-living energy intake in the subsequent 38 h remained less after VHI compared with CON and MC (P <= 0.050). These observations were associated with lower active ghrelin (P <= 0.050), higher blood lactate (P <= 0.014) and higher blood glucose (P <= 0.020) after VHI compared with all other trials. Despite higher heart rate and ratings of perceived exertion (RPE) during HI and VHI compared with MC (P <= 0.004), ratings of physical activity enjoyment were similar between all the exercise trials (P = 0.593). No differences were found in perceived appetite between trials. CONCLUSIONS: High-intensity intermittent exercise suppresses subsequent ad-libitum energy intake in overweight inactive men. This format of exercise was found to be well tolerated in an overweight population.