Pd-catalyzed gem-difluoroallylation of arylboronic acids with γ,γ-difluoroallylic acetates

被引：34

作者：

Zhang, Bo ^{[1
]}

Zhang, Xingang ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, Shanghai 200032, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2016年 / 52卷 / 06期

基金：

中国国家自然科学基金;

关键词：

ARYL BORONIC ACIDS; NUCLEOPHILIC-SUBSTITUTION; REDUCTIVE ELIMINATION; PALLADIUM; INHIBITORS; BOND; ALPHA; ALPHA-DIFLUOROKETONES; DERIVATIVES; COMPLEXES; FLUORINE;

D O I：

10.1039/c5cc08394j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A highly regio- and stereo-selective palladium-catalyzed gem-difluoroallylation of arylboronic acids with gamma,gamma-difluoroallylic acetates has been described. The method allows the synthesis of a variety of gem-difluoroallylated arenes with a tosyloxy group on the C=C double bond, thus providing a good opportunity for down-stream transformations.

引用

页码：1238 / 1241

页数：4

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