We present here the experimental and numerical results to demonstrate the superior performance of optical wavelet-matched filtering over conventional matched filtering. For this purpose, the biomolecule material bacteriorhodopsin (bR) as the recording media and the improved dual-axis joint transform correlator configuration as the preferred optical setup have been used. Compared with the dual-axis joint Fourier transform correlator, the dual-axis joint wavelet transform correlator provides better correlation performance. (C) 1997 Optical Society of America.