Sequential Addition and Cyclization Processes of α,β-Ynones and α,β-Ynoates Containing Proximate Nucleophiles

被引：40

作者：

Abbiati, Giorgio ^{[1
]}

Arcadi, Antonio ^{[2
]}

Marinelli, Fabio ^{[2
]}

Rossi, Elisabetta ^{[1
]}

机构：

[1] Univ Milan, Dipartimento Sci Farmaceut, Sez Chim Gen & Organ A Marchesini, I-20133 Milan, Italy

[2] Univ Aquila, Dipartimento Sci Fis & Chim, I-67010 Laquila, Italy

来源：

SYNTHESIS-STUTTGART | 2014年 / 46卷 / 06期

关键词：

aminoalkynones; hydroxyalkynoates; sequential reactions; annulation; heterocycles; RHODIUM-CATALYZED ADDITION; HIGHLY SUBSTITUTED FURANS; ALPHA; BETA-UNSATURATED CARBONYL-COMPOUNDS; POT 3-COMPONENT SYNTHESIS; ALPHA-AMINO ESTERS; EFFICIENT SYNTHESIS; ARYLBORONIC ACIDS; ARYL IODIDES; GAMMA-HYDROXY-ALPHA; BETA-ACETYLENIC ESTERS; ELECTROPHILIC CYCLIZATION;

D O I：

10.1055/s-0033-1338594

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This review examines sequential processes involving alpha,beta-ynones and alpha,beta-ynoates containing proximate nucleophiles as useful building blocks for the synthesis of heterocyclic derivatives through conjugate-addition-type, pericyclic and transition-metal-catalyzed transfer hydrogenation, hydroarylation, hydrovinylation, or hydroalkynylation reactions followed by heterocyclization.

引用

页码：687 / 721

页数：35

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