Risk factors for colonization with carbapenemase-producing Klebsiella pneumoniae in hospital: A matched case-control study

被引:14
作者
Gagliotti, Carlo [1 ]
Giordani, Stefano [2 ]
Ciccarese, Vincenzo [2 ]
Barozzi, Agostino [2 ]
Giovinazzi, Antonio [3 ]
Pietrantonio, Anne Marie [2 ]
Moro, Maria Luisa [1 ]
Pinelli, Giovanni [2 ]
Sarti, Mario [2 ]
机构
[1] Agenzia Sanitaria & Sociale Reg Emilia Romagn, I-40127 Bologna, Italy
[2] Nuovo Osped Civile S Agostino Estense, Modena Hlth Trust, Baggiovara, Italy
[3] Univ Modena & Reggio Emilia, Dept Diagnost Clin & Publ Hlth Med, Modena, Italy
关键词
Carbapenemase; Klebsiella pneumoniae; Carrier; Antibiotic prescription; RESISTANT ENTEROBACTERIACEAE; CLINICAL EPIDEMIOLOGY; ACQUISITION;
D O I
10.1016/j.ajic.2014.05.028
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
The present case-control study aimed to identify the main factors associated with colonization with carbapenemase-producing Klebsiella pneumoniae (CPKP) in acute care facilities. Administration of carbapenems (odds ratio [OR], 3.67; 95% confidence interval [CI], 1.37-9.83) and other antibiotics (OR, 2.83; 95% CI, 1.10-7.31) during the hospital stay was significantly associated with outcome. The design of this study, with concurrent selection of controls and matching by hospital ward and date of screening, provides a more accurate estimation of relative risks for CPKP colonization than previous investigations. Copyright (C) 2014 by the Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.
引用
收藏
页码:1006 / 1008
页数:3
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