Microviridins, elastase inhibitors from the cyanobacterium Nostoc minutum (NIES-26)

被引：56

作者：

Murakami, M ^{[1
]}

Sun, Q ^{[1
]}

Ishida, K ^{[1
]}

Matsuda, H ^{[1
]}

Okino, T ^{[1
]}

Yamaguchi, K ^{[1
]}

机构：

[1] UTSUNOMIYA UNIV,DEPT APPL BIOCHEM,UTSUNOMIYA,TOCHIGI 321,JAPAN

来源：

PHYTOCHEMISTRY | 1997年 / 45卷 / 06期

关键词：

Nostoc minutum; Cyanophyceae; cyclic peptide; microviridin G; microviridin H; elastase inhibitor; protease inhibitor;

D O I：

10.1016/S0031-9422(97)00131-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two new microviridin-type peptides were isolated from the freshwater cyanobacterium Nostoc minutum (NIES-26), which we named microviridin G and H. Their structures were shown to be 1 and 2 respectively, on the basis of 2D NMR data and chemical degradation. These peptides inhibited elastase potently. (C) 1997 Elsevier Science Ltd. All rights reserved.

引用

页码：1197 / 1202

页数：6