Microviridins, elastase inhibitors from the cyanobacterium Nostoc minutum (NIES-26)

被引：56
|
作者：
Murakami, M [1 ]
Sun, Q [1 ]
Ishida, K [1 ]
Matsuda, H [1 ]
Okino, T [1 ]
Yamaguchi, K [1 ]
机构：
[1] UTSUNOMIYA UNIV,DEPT APPL BIOCHEM,UTSUNOMIYA,TOCHIGI 321,JAPAN
来源：
PHYTOCHEMISTRY | 1997年 / 45卷 / 06期
关键词：
Nostoc minutum; Cyanophyceae; cyclic peptide; microviridin G; microviridin H; elastase inhibitor; protease inhibitor;
D O I：
10.1016/S0031-9422(97)00131-3
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Two new microviridin-type peptides were isolated from the freshwater cyanobacterium Nostoc minutum (NIES-26), which we named microviridin G and H. Their structures were shown to be 1 and 2 respectively, on the basis of 2D NMR data and chemical degradation. These peptides inhibited elastase potently. (C) 1997 Elsevier Science Ltd. All rights reserved.
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收藏
页码：1197 / 1202
页数：6
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