Iron-Catalyzed Allylic C-H Amination of Substituted 1,3-Dienes

被引：19

作者：

Murru, Siva ^{[1
]}

Srivastava, Radhey S. ^{[1
]}

机构：

[1] Univ Louisiana Lafayette, Dept Chem, Lafayette, LA 70504 USA

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2014年 / 2014卷 / 10期

关键词：

Homogeneous catalysis; Amination; Allylic compounds; Iron; Dienes; Chemoselectivity; SITE-SELECTIVE SP(2); DIELS-ALDER ADDUCTS; TERMINAL OLEFINS; HOMOALLYLIC DIAMINATION; REDUCTIVE ANNULATION; ALKENES; PALLADIUM; COMPLEXES; BONDS; FUNCTIONALIZATION;

D O I：

10.1002/ejoc.201301914

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A catalytic method for the selective allylic C-H amination of dienes and trienes using arylhydroxylamines has been developed. This iron-catalyzed approach involves the in situ generation of activated nitrosoarenes, which in turn react with dienes or trienes to give the corresponding aminomethyl dienes or trienes as the major products, and hetero-Diels-Alder adducts as minor products. The selectivity depends on the structures of both the catalyst and the substrate. We have also studied substituent effects using p-substituted phenylhydroxylamines.

引用

页码：2174 / 2181

页数：8

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