Ocular complications of cancer therapy: a primer for the ophthalmologist treating cancer patients

被引:18
作者
Hazin, Ribhi [4 ]
Abuzetun, Jamil Y. [3 ]
Daoud, Yassine J. [2 ]
Abu-Khalaf, Maysa M. [1 ]
机构
[1] Yale Univ, Sch Med, Yale Canc Ctr, Sect Med Oncol, New Haven, CT 06520 USA
[2] Duke Univ, Med Ctr, Ctr Eye, Durham, NC 27710 USA
[3] Duke Univ, Med Ctr, Dept Internal Med, Durham, NC 27710 USA
[4] Harvard Univ, Fac Arts & Sci, Cambridge, MA 02138 USA
关键词
cancer; cataracts; chemotherapy; conjunctivitis; dry eye syndrome; glaucoma; ocular complications; radiation therapy; DRY EYE; BREAST-CANCER; ALLERGIC CONJUNCTIVITIS; INTRAOCULAR-PRESSURE; RADIATION CATARACTS; ADJUVANT TREATMENT; FLUID RETENTION; LACRIMAL GLAND; GLAUCOMA; DOCETAXEL;
D O I
10.1097/ICU.0b013e32832c9007
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose of review Cancer patients may develop ocular complications secondary to direct or metastatic involvement with cancer, radiation exposure, or chemotherapy. As many as 1.4 million new cancer cases arise in the United States annually. Recent findings Chemotherapy administration remains a critical aspect of treating many cancers and offers improved prognosis and prolonged survival in many cases; however, these therapies are known to cause a wide range of toxicities. Summary Ocular side effects such as photophobia, cataracts, glaucoma, retinopathy, and other ocular toxicities have been reported following chemotherapy administration. To effectively treat cancer patients, oncologists, primary care clinicians, and ophthalmologists should be aware of the potential ophthalmic toxicities certain widely used chemotherapeutic agents and radiation therapy may pose to their patients, particularly in the setting of preexisting ocular conditions.
引用
收藏
页码:308 / 317
页数:10
相关论文
共 61 条
[61]  
Wolf N, 2008, MOL VIS, V14, P274