Synthesis and characterisation of chitosan-graft-poly(OEGMA) copolymers prepared by ATRP

被引：43

作者：

Munro, Natasha H. ^{[1
]}

Hanton, Lyall R. ^{[1
]}

Moratti, Stephen C. ^{[1
]}

Robinson, Brian H. ^{[1
]}

机构：

[1] Univ Otago, Dept Chem, Dunedin 9054, New Zealand

来源：

CARBOHYDRATE POLYMERS | 2009年 / 77卷 / 03期

关键词：

Chitosan; ATRP; Graft copolymers; GRAFT-COPOLYMERIZATION; RADICAL POLYMERIZATION; POLY(ETHYLENE GLYCOL); CHITOSAN DERIVATIVES; SIDE-CHAINS; CHITIN;

D O I：

10.1016/j.carbpol.2009.01.026

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Two synthetic routes, "grafting-from" and "grafting-to" the chitosan backbone, were investigated to prepare chitosan-graft-poly(OEGMA) copolymers by ATRP. The copolymers were characterised by (1)H NMR and FT-IR spectroscopy, elemental analyses and GPC. Estimates of the degree of grafting were quantitatively found from integration of the (1)H NMR spectra. The GPC data indicated that the hydrodynamic volumes of the polymers were significantly altered by the incorporation of poly(OEGMA). A comparison of the two synthetic methods showed differences in the ratio of synthetic and natural polymers present in the resulting combs. The "grafting-to" synthetic route was preferable as the polymers were of higher purity and more defined. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：496 / 505

页数：10

共 27 条

[1] THE DEVELOPMENT OF VERSION-3 AND VERSION-4 OF THE CAMBRIDGE STRUCTURAL DATABASE SYSTEM [J].