Influence of Precursors and Inhibitor on the Production of Extracellular 5-Aminolevulinic Acid and Biomass by Rhodopseudomonas palustris KG31

被引：28

作者：

Saikeur, Angkana ^{[1
]}

Choorit, Wanna ^{[1
]}

Prasertsan, Poonsuk ^{[2
]}

Kantachote, Duangporn ^{[3
]}

Sasaki, Ken ^{[4
]}

机构：

[1] Walailak Univ, Sch Agr Technol, Nakhon Si Thammarat 80161, Thailand

[2] Prince Songkla Univ, Fac Agroind, Songkhla 90112, Thailand

[3] Prince Songkla Univ, Fac Sci, Songkhla 90112, Thailand

[4] Hiroshima Int Sch, Fac Engn, Hiroshima 7390321, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2009年 / 73卷 / 05期

关键词：

5-aminolevulinic acid; Box-Behnken design; response surface methodology; RECOMBINANT ESCHERICHIA-COLI; DELTA-AMINOLEVULINIC-ACID; RHODOBACTER-SPHAEROIDES; LEVULINIC ACID; CULTURE; PORPHOBILINOGEN; SUPPLEMENT; LIGHT;

D O I：

10.1271/bbb.80682

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

5-Aminolevulinic acid (ALA) and the biomass of photosynthetic bacteria, Rhodopseudomonas palustris KG31, have very high potential for development and exploitation as bioherbicide and biofertilizer respectively. In this work, the effects of two precursors and an inhibitor of aminolevulinic dehydratase (ALAD) added to the VFA culture medium on the production of ALA and biomass were investigated. The experimental runs were carried out according to a Box-Behnken design. The precursors were added to the medium at the beginning of cultivation, while the inhibitor was added after 24h. Statistical analysis indicated that levulinic acid (LA) has a positive effect on ALA production while glycine has a negative effect on biomass production. In order to enhance both ALA and biomass products, the most suitable medium was VFA medium supplemented with 3.0 mM glycine and 10 mM LA, giving ALA and biomass of 182.91 mu m and 3.1 gDCW/l within 54 h.

引用

页码：987 / 992

页数：6

共 27 条

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BIOTECHNOLOGY LETTERS, 1993, 15 (08) : 859 - 864
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Chung, SY
Seo, KH
Rhee, JI
PROCESS BIOCHEMISTRY, 2005, 40 (01) : 385 - 394
[24] Effects of 5-aminolevulinic acid (ALA)-containing supernatants from selected Rhodopseudomonas palustris strains on rice growth under NaCl stress, with mediating effects on chlorophyll, photosynthetic electron transport and antioxidative enzymes
Nunkaew, Tomorn
Kantachote, Duangporn
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ELECTRONIC JOURNAL OF BIOTECHNOLOGY, 2014, 17 (01): : 19 - 26
[25] Simultaneous Promotion of Microalgal CO2 Assimilation, Biomass Accumulation, Lipid Production, and Wastewater Nutrient Removal by Adding 5-Aminolevulinic Acid
Li, Yongfu
Qiu, Ziyue
Cui, Hongwu
Wang, Lu
Zhang, Litao
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2022, 10 (45) : 14715 - 14723
[26] Improvement of 5-aminolevulinic acid production by Rubrivivax benzoatilyticus PS-5 with self-flocculation by co-fermentation of precursors and volatile fatty acids under pH-controlled conditions
Sattayasamitsathit, Supalak
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ANNALS OF MICROBIOLOGY, 2014, 64 (01) : 385 - 389
[27] Improvement of 5-aminolevulinic acid production by Rubrivivax benzoatilyticus PS-5 with self-flocculation by co-fermentation of precursors and volatile fatty acids under pH-controlled conditions
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Annals of Microbiology, 2014, 64 : 385 - 389

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