Microarrays of heparin oligosaccharides obtained by nitrous acid depolymerization of isolated heparin

被引:45
作者
de Paz, Jose L.
Spillmann, Dorothe
Seeberger, Peter H.
机构
[1] ETH, Swiss Fed Inst Technol, Organ Chem Lab, CH-8093 Zurich, Switzerland
[2] Uppsala Univ, Dept Med Biochem & Microbiol, SE-75123 Uppsala, Sweden
关键词
D O I
10.1039/b605318a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Heparin oligosaccharides derived by nitrous acid depolymerization of heparin have been immobilized on amine-coated glass slides. The formation of a Schiff base creates heparin chips that are a suitable platform for the high-throughput analysis of carbohydrate - protein interactions.
引用
收藏
页码:3116 / 3118
页数:3
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